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Interstitial Lung Disease

Under the directorship of Dr. Jad Kebbe, OU developed the first and only comprehensive ILD program in the state of Oklahoma. The program is composed of a multidisciplinary team of experts in pulmonary medicine, rheumatology, thoracic radiology and pathology. This team leads a twice monthly multidisciplinary ILD meeting to discuss new and challenging cases, both for education purposes and to generate recommendations for diagnosis and management. Fellows from both pulmonology and rheumatology participate by presenting cases, engage in a high-yield expert-led discussion, and learn by reviewing high resolution CT scan images, serologies and pathology slides.

Under the guidance of Dr. Salim Daouk, the OU ILD clinic has become a member of WASOG: The World Association of Sarcoidosis and Other Granulomatous disorders. Close partnership with the Oklahoma Medical Research Foundation (OMRF) offers advanced clinical and research opportunities.

There are ample occasions for clinical and translational research in ILD. Our multidisciplinary team garnered national and local grant funding, and participates in registries and pharmaceutical industry research. In addition, the ILD experts at OU perform transbronchial cryobiopsy when needed for diagnosis. OU Medical Center is a certified center for treatment of Pulmonary Alveolar Proteinosis by whole lung lavage.

Common types of ILD encountered at OU are as follows:

Idiopathic Interstitial Pneumonia

  • Acute Interstitial Pneumonia
  • Familial Pulmonary Fibrosis
  • Idiopathic Pulmonary Fibrosis (IPF)
  • Non-Specific Interstitial Pneumonia (NSIP)
  • Cryptogenic Organizing Pneumonia
  • Idiopathic Pleuroparenchymal Fibroelastosis
  • Lymphocytic Interstitial Pneumonia

ILDs Related to Tobacco Use

  • Desquamative Interstitial Pneumonia
  • Pulmonary Langerhans Cell Histiocytosis
  • Respiratory Bronchiolitis-Interstitial Lung Disease (RB-ILD)

Pulmonary Manifestations of Connective Tissue Diseases

  • Granulomatosis with Polyangiitis
  • Idiopathic Pneumonia with Autoimmune Features (IPAF)
  • Microscopic Polyangiitis
  • Mixed Connective Tissue Disease
  • Polymyositis/Dermatomyositis/Antisynthetase syndrome
  • Rheumatoid Arthritis
  • Scleroderma
  • Sjögren
  • Systemic Lupis Erythematosus

Other Interstitial Lung Diseases

  • Acute Eosinophilic Pneumonia
  • Chronic Eosinophilic Pneumonia
  • Drug-Induced Lung Disease
  • Hypersensitivity Pneumonitis
  • Lymphangioleiomyomatosis (LAM)
  • Pulmonary Alveolar Proteinosis (PAP)
  • Occupational and Environmental ILDs: Asbestosis, Silicosis, Coal Worker’s Pneumoconiosis, Berylliosis (Chronic Beryllium Disease)
  • Post-Inflammatory Pulmonary Fibrosis
  • Sarcoidosis

 

Information for Patients:

Interstitial Lung Disease (ILD) refers to a broad group of more than 200 different lung disorders that cause lung inflammation or scarring (fibrosis). Common symptoms include shortness of breath and unrelenting dry cough. They be classified into idiopathic interstitial pneumonias (no known cause), some of which are related to tobacco use, ILDs associated with connective tissue diseases (such as rheumatoid arthritis, lupus, scleroderma…), and other ILDs some of which are related to environmental and occupational exposures (asbestos, coal, silica…). Sarcoidosis is a specific type of ILD, which can cause granulomatous inflammation in several organs in addition to the lungs.

If you are a patient, our team of experts is ready to meet with you, review your history, perform a thorough examination and help you find the right diagnosis and treatment. If you wish to receive dedicated, personal and specialized care by Dr. Kebbe or Dr. Daouk, please call the ILD clinic located at:

OU Physicians
825 NE 10th St, Suite 2E
Oklahoma City, OK 73104
Phone: 405-271-7001

Fax: 405-271-7034

 

For more information:

Dr. Kebbe: https://findadoc.oumedicine.com/jad-kebbe
Dr. Daouk: https://findadoc.oumedicine.com/salim-daouk

 

A list of publications can be found at the following links:

Dr. Kebbe: https://pubmed.ncbi.nlm.nih.gov/?term=kebbe+j
Dr. Daouk: https://pubmed.ncbi.nlm.nih.gov/?term=Daouk+Saleem