Interstitial Lung Disease (ILD) refers to a broad group of more than 200 different lung disorders that cause lung inflammation or scarring (fibrosis). Common symptoms include shortness of breath and unrelenting dry cough. ILDs can be classified into idiopathic interstitial pneumonias, some of which are related to tobacco use, ILDs associated with connective tissue diseases, and other ILDs some of which are related to environmental and occupational exposures. Sarcoidosis is a specific type of ILD, which can cause granulomatous inflammation in several organs in addition to the lungs.
Since diagnosis can be challenging, OU has developed the only ILD program in the state of Oklahoma. The program is composed of a multidisciplinary team of experts in pulmonary medicine, rheumatology, thoracic radiology, pathology and surgery. This team of specialists meets twice a month to discuss several cases in order to make recommendations for diagnosis and management. Fellows from both pulmonology and rheumatology participate by presenting cases and learn by reviewing high resolution CT scan images and pathology slides.
The OU ILD clinic is also a member of WASOG: The World Association of Sarcoidosis and Other Granulomatous disorders. Close partnership with the Oklahoma Medical Research Foundation (OMRF) offers advanced clinical and research opportunities.
There are ample opportunities for clinical and translational research in ILD. In addition, the ILD experts at OU perform cryobiopsy when needed for diagnosis. OU is also a certified center for treatment of Pulmonary Alveolar Proteinosis by whole lung lavage.
Common types of ILD encountered at OU are as follows:
Idiopathic Interstitial Pneumonia
ILDs Related to Tobacco Use
- Desquamative Interstitial Pneumonia
- Pulmonary Langerhans Cell Histiocytosis
- Respiratory Bronchiolitis-Interstitial Lung Disease (RB-ILD)
Pulmonary Manifestations of Connective Tissue Diseases
- Granulomatosis with Polyangiitis
- Idiopathic Pneumonia with Autoimmune Features (IPAF)
- Microscopic Polyangiitis
- Mixed Connective Tissue Disease
- Polymyositis/Dermatomyositis/Antisynthetase syndrome
- Rheumatoid Arthritis
- Systemic Lupus Erythematosus
Other Interstitial Lung Diseases