https://medicine.ouhsc.edu/Academic-Departments Parent Page: Academic Departments id: 22046 Active Page: Faculty - Staffid:22079

Faculty and Staff

Faculty

Gregory Blakey, MD

Gregory Blakey, MD

Vice Chair and Associate Professor
Presbyterian Health Foundation Chair in Pathology
Director of Molecular Genetic Pathology Fellowship Program
Vice Chief of Pathology Services and Director of Clinical
Pathology, OU Medical System

Kenneth E Blick, PhD

Kenneth E. Blick, PhD

Professor of Pathology

Director of Clinical Chemistry

Director of Immunoassay/Endocrine Laboratories

William Brinkley, DVM

William Brinkley, DVM

Associate Professor

Director, Rodent Resources Program

Chelsey D. Deel, MD

Chelsey D. Deel, MD

Assistant Professor
Department of Pathology

Wei-Qun Ding, PhD

Wei-Qun Ding, PhD

Associate Professor of Experimental Pathology 
Research/Molecular Oncology

S. Terence Dunn, PhD

S. Terence Dunn, PhD

Laboratory Director of Molecular Pathology

Kar-Ming Fung, MD, PhD

Kar-Ming Fung, MD, PhD

Professor Neuropathology/Surgical Pathology
Adjunct Professor Urology
Director of Neuropathology
Director of Electron Microscopy

Bradley C Gehrs, MD

Bradley C. Gehrs, MD

Interim Director of Transfusion Services

Assistant Professor of Pathology

Staff Pathologist, OU Medical Center

Asish K. Ghosh, PhD

Asish K. Ghosh, PhD

Associate Professor of Medicine

Elizabeth M Gillies, MD

Elizabeth M. Gillies, MD

Associate Professor, Pathology

Director of Surgical Pathology

Director, Pathology Programs, Department of Otorhinolaryngology

Lewis A Hassell, MD

Lewis A. Hassell, MD

Professor of Pathology

Professor of Excellence in Anatomic Pathology

Director, Anatomic Pathology

Yuechueng Liu, PhD

Yuechueng Liu, PhD

Associate Professor of Pathology

Wenyi Luo, MD, PhD

Wenyi Luo, MD, PhD

Assistant Professor

Michael Magguilli, MD, MS

Michael Magguilli, MD, MS

Assistant Professor of Pathology
Director of Autopsy Services and Education
Autopsy, Cytopathology, and Surgical Pathology

Cindy McCloskey, MD

Cindy McCloskey, MD

Associate Professor of Pathology

Pathology Residency Program Director

Director, Microbiology and Virology Laboratories
OU Medical Center

Priyabrata Mukherjee, PhD, FRSC

Priyabrata Mukherjee, PhD, FRSC, FAIMBE, FNAI

PHF Presidential Professor

Associate Director of Translational Research, Stephenson Cancer Center

Peggy and Charles Stephenson Endowed Chair in Laboratory Cancer Research

Professor of Pathology

Co-Director, Nanomedicine Program, Stephenson Cancer Center

Oklahoma TSET Research Scholar

Aravindan Natarajan

Aravindan Natarajan, MS., MPhil., PhD., CCA.

Associate Professor, Department of Radiation Oncology,
Associate Professor (Adjunct), Department of Anesthesiology,
Associate Professor (Adjunct), Department of Pathology
Course Director, Radiation Biology for Radiation Oncology Residents
Graduate Faculty, College of Medicine
Member, Cancer Biology Program

James Papin, PhD

James Papin, PhD

Assistant Professor, OUHSC Dept. of Pathology
Associate Scientist, Oklahoma Medical Research Foundation

Jo Elle Peterson, MD

Jo Elle Peterson, MD

Assistant Professor

Rajagopal Ramesh, PhD

Rajagopal Ramesh, PhD

Jim and Christy Everest Endowed Chair in Cancer Developmental Therapeutics
Professor of Pathology
Director, Experimental Therapeutics and Translational Cancer Medicine
Chair, Fellowship Training and Mentoring Program
Member, OU Cancer Institute

Maria Ruiz-Echevarria, PhD

Maria Ruiz-Echevarria, PhD

Associate Professor, Department of Pathology

Associate Professor (Adjunct), Department of Medicine

Graduate Faculty, College of Medicine

Associate Member, Stephenson Cancer Center

Ravi Sawh, MB, BS, DM

Ravi Sawh, MB, BS, DM

Assistant Professor
Site Coordinator for Resident Training
Chief, Pathology and Laboratory Medicine Service
Oklahoma City VA Health Care System, Oklahoma City, OK

Teresa Scordino, MD

Teresa Scordino, MD

Assistant Professor

Associate Director, Hempath

Dena Shibib, DO

Dena Shibib, DO

Assistant Professor

Michael Talbert, MD

Michael Talbert, MD

Lloyd E. Rader Professor and Chairman, Department of Pathology 

Chief of Pathology Services and Laboratory Director
OU Medical System

Takemi Tanaka, Ph.D.

Takemi Tanaka, Ph.D.

Associate Professor

Cody Thomas, MD

Cody Thomas, MD

Assistant Professor of Pathology

Henry Tran, MD

Henry Tran, MD

Assistant Professor

Elizabeth Wellberg, BS, PhD

Elizabeth Wellberg, BS, PhD

Assistant Professor

Department of Pathology

Harold Hamm Diabetes Center

Stephenson Cancer Center

Roman F Wolf, DVM

Roman F. Wolf, DVM

Assistant Director, Division of Comparative Medicine

Associate Professor, Pathology

Contract Veterinarian, Animal Resources Facility, Veterans Administration Medical Center, Oklahoma City

Jie Wu, PhD

Jie Wu, PhD

Professor of Pathology
Peggy and Charles Stephenson Endowed Chair in Cancer Translational Research
Co-leader, Cell Signaling and Oncogenes Team, Stephenson Cancer Center
Oklahoma TSET Research Scholar

Zhongxin Yu, MD

Zhongxin Yu, MD

Associate Professor of Pathology

Oklahoma State Association of Pathologists Professorship

Director, Pediatric Pathology

Director, Pediatric Autopsy Service

Roy Zhang, MD

Roy R. Zhang, MD

Assistant Professor of Pathology

Joe Zhao, PhD

Joe Zhao, PhD

Alfred M. Shideler Professor of Pathology 
Director, Experimental Pathology 
Director, Pathology Graduate Program

Rosemary Zuna, MD

Rosemary Zuna, MD

Section Head, Gynecologic Pathology

Professor of Pathology

Adjunct Faculty

Yuechueng Liu, PhD
Pathology

Yuechueng Liu, PhD

Associate Professor of Pathology


The University of Oklahoma
Health Sciences Center
O'Donoghue Research Bulding
1122 N.E. 13th St
Rm 326
Oklahoma City, Oklahoma  73104

405-271-2336

yuechueng-liu@ouhsc.edu


Education:

  • Wuhan University
    China
    B.S. - Biochemistry (1982)
  • University of Miami
    Miami, Florida
    Ph.D. - Biochemistry/Molecular Biology (1988)


Clinical/Research Interests:

  • Neuronal signal transduction
  • Axonal growth and regeneration
  • Neurotransmitter release
  • Neural degenerative diseases

Our laboratory is interested in the molecular basis of synaptic transmission in the nervous system. Many neurological disorders including depression and schizophrenia may involve changes in synaptic transmission. For instance, it has been suggested that excess dopaminergic transmission may contribute to the development of schizophrenia. The mechanism of how neurons release transmitters in response to stimuli is poorly understood. Several proteins in the synaptic terminals have been suggested to be important for the docking and fusion of the synaptic vesicles. It is hypothesized that these proteins form the core structure for synaptic vesicle fusion/docking. One of the synaptic proteins that we are currently studying is SNAP-25. We have prepared a number of mutant SNAP-25 and have introduced the mutant DNA clones into neuronal cells. The effect of the mutant SNAP-25 on neurotransmitter release will be studied in these cells. Another project in the laboratory is to identify novel proteins that may be complexed with SNAP-25. Several techniques such as immuno-affinity purification and chemical cross-linking are used to isolate the putative SNAP-25 associated proteins. We hope our work will provide new information regarding neurotransmitter release, and will eventually allow us to study the more complex synaptic transmission in the central nervous system.


Select Publications:

  1. Xia Z, and Liu Y.  Reliable and global measurement of fluorescence resonance energy transfer using fluorescence microscopes.   Biophy. J.  2001; 81: 2395-2402.

  2. Karvar S, Yao X, Duman JG, Hybiske K, Liu Y, and Forte JG.  Intracellular distribution and functional importance of vesicle-associated membrane protein-2 in gastric parietal cells.  Gastroenterol.  2002; 123: 281-290.

  3. Xiao J, Zhou Q, and Liu Y.  A variant PC12 cell line that spontaneously differentiates and extends neuritic processes.  J. Neurosci. Res.  2002 Jul 1; 69 (1): 104-109.

  4. Karvar S, Yao X, Crothers JM, Liu Y, and Forte JG.  Localization and function of soluble N-ethylmaleimide-sensitive factor attachment protein-25 and vesicle-associated membrane protein-2 in functioning gastric parietal cells.  J. Biol. Chem.  2002 Dec 20; 277 (51): 50030-50035.

  5. Xiao J, and Liu Y.  Differential roles of ERK and JNK in early and late stages of neuritogenesis, a study in a novel PC12 model system.  J. Neurochem. 2003 Sep;86(6):1516-23.

  6. Xiao J, Xia Z, Pradhan A, Zhou Q, and Liu Y.  An immunochemical method that distinguishes free from complexed SNAP-25 in vivo.  J Neurosci Res. 2004 Jan 1;75(1):143-51.

  7. Wei Q, Zhang F, Richardson MM, Roy NH, Rodgers W, Liu Y, Zhao WY, Fu CY, Ding YJ, Huang C, Chen YJ, Sun Y, Ding LX, Hu Y, Ma JX, Boulton ME, Pasula S, Wren JD, Tanaka S, Huang XL, Thali M, Hamerlin GJ, Zhang XA. CD82 restrains angiogenesis by altering lipid raft clustering and CD44 trafficking in endothelial cells. Circulation. 2014 Oct 21;130(17):1493-504. doi: 10.1161/CIRCULATIONAHA.114.011096. Epub 2014 Aug 22.  PMID: 25149363