https://medicine.ouhsc.edu/academic-departments Parent Page: Academic Departments id: 22046 Active Page: Faculty - Staffid:22079

Faculty and Staff

Faculty

Laura Adhikari, MD

Laura Adhikari, MD

Assistant Professor

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Sepideh Nikki Asadbeigi, MD

Sepideh N Asadbeigi, MD

Assistant Professor - Pathology

Dermatopathology

Adjunct Faculty - Dermatology

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Gregory Blakey, MD

Gregory Blakey, MD

Vice Chair and Associate Professor
Presbyterian Health Foundation Chair in Pathology
Director of Molecular Genetic Pathology Fellowship Program
Vice Chief of Pathology Services and Director of Clinical
Pathology, OU Medical System

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William Brinkley, DVM

William Brinkley, DVM

Associate Professor

Director, Rodent Resources Program

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Chelsey D. Deel, MD

Chelsey D. Deel, MD

Assistant Professor
Department of Pathology

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Wei-Qun Ding, PhD

Wei-Qun Ding, PhD

Professor of Experimental Pathology 
Research/Molecular Oncology

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S. Terence Dunn, PhD

S. Terence Dunn, PhD

Laboratory Director of Molecular Pathology

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Kar-Ming Fung, MD, PhD

Kar-Ming Fung, MD, PhD

Professor Neuropathology/Surgical Pathology

Director of Anatomic Pathology

Adjunct Professor Urology
Director of Neuropathology
Director of Electron Microscopy

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Bradley C Gehrs, MD

Bradley C. Gehrs, MD

Interim Director of Transfusion Services

Assistant Professor of Pathology

Staff Pathologist, OU Medical Center

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Asish K. Ghosh, PhD

Asish K. Ghosh, PhD

Associate Professor of Medicine

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Elizabeth M Gillies, MD

Elizabeth M. Gillies, MD

Associate Professor, Pathology

Director of Surgical Pathology

Director, Pathology Programs, Department of Otorhinolaryngology

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Lewis A Hassell, MD

Lewis A. Hassell, MD

Professor of Pathology

Professor of Excellence in Anatomic Pathology

Director, Anatomic Pathology

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Michael Magguilli, MD, MS

Michael Magguilli, MD, MS

Assistant Professor of Pathology
Director of Autopsy Services and Education
Autopsy, Cytopathology, and Surgical Pathology

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Jeffrey McBride, MD, PhD

Jeffrey McBride, MD, PhD

Assistant Professor

Director of Dermatopathology

Adjunct Faculty - Pathology

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Cindy McCloskey, MD

Cindy McCloskey, MD

Associate Professor of Pathology
Director, Microbiology and Virology Laboratories, OU Medical Center

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Priyabrata Mukherjee, PhD, FRSC

Priyabrata Mukherjee, PhD, FRSC, FAIMBE, FAAAS, FNAI

PHF Presidential Professor

Associate Director of Translational Research, Stephenson Cancer Center

Peggy and Charles Stephenson Endowed Chair in Laboratory Cancer Research

Professor of Pathology

Co-Director, Nanomedicine Program, Stephenson Cancer Center

Oklahoma TSET Research Scholar

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James F. Papin, PhD

James F. Papin, PhD

Associate Vice President for Health Sciences Research

Associate Professor of Pathology
Director, Institutional Research Core Facility
Associate Director and Head of Technical Services, Division of Comparative Medicine

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Jo Elle Peterson, MD

Jo Elle Peterson, MD

Assistant Professor

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Rajagopal Ramesh, PhD

Rajagopal Ramesh, PhD

Jim and Christy Everest Endowed Chair in Cancer Developmental Therapeutics
Professor of Pathology
Director, Experimental Therapeutics and Translational Cancer Medicine
Chair, Fellowship Training and Mentoring Program
Member, OU Cancer Institute

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Geeta Rao, PhD

Geeta Rao, PhD

Assistant Professor

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Maria Ruiz-Echevarria, PhD

Maria Ruiz-Echevarria, PhD

Associate Professor, Department of Pathology

Associate Professor (Adjunct), Department of Medicine

Graduate Faculty, College of Medicine

Associate Member, Stephenson Cancer Center

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Ravi Sawh, MB, BS, DM

Ravi Sawh, MB, BS, DM

Assistant Professor
Site Coordinator for Resident Training
Chief, Pathology and Laboratory Medicine Service
Oklahoma City VA Health Care System, Oklahoma City, OK

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Teresa Scordino, MD

Teresa Scordino, MD

Assistant Professor

Associate Director, Hempath

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Dena Shibib, DO

Dena Shibib, DO

Assistant Professor, Department of Pathology
Associate Director, Microbiology and Virology Laboratories, OU Health
Director, Microbiology Laboratory, Oklahoma City VA Health Care System

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Michael Talbert, MD

Michael Talbert, MD

Lloyd E. Rader Professor and Chairman, Department of Pathology 

Chief of Pathology Services and Laboratory Director
OU Medical System

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Takemi Tanaka, Ph.D.

Takemi Tanaka, Ph.D.

Professor

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Cody Thomas, MD

Cody Thomas, MD

Assistant Professor of Pathology

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Henry Tran, MD

Henry Tran, MD

Assistant Professor

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Elizabeth Wellberg, BS, PhD

Elizabeth Wellberg, BS, PhD

Assistant Professor

Department of Pathology

Harold Hamm Diabetes Center

Stephenson Cancer Center

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Roman F Wolf, DVM

Roman F. Wolf, DVM

Assistant Director, Division of Comparative Medicine

Associate Professor, Pathology

Contract Veterinarian, Animal Resources Facility, Veterans Administration Medical Center, Oklahoma City

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Jie Wu, PhD

Jie Wu, PhD

Professor of Pathology
Peggy and Charles Stephenson Endowed Chair in Cancer Translational Research
Co-leader, Cell Signaling and Oncogenes Team, Stephenson Cancer Center
Oklahoma TSET Research Scholar

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Zhongxin Yu, MD

Zhongxin Yu, MD

Professor of Pathology

Oklahoma State Association of Pathologists Endowed Professor

Director, Pediatric Pathology

Director, Pediatric Autopsy Service

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Joe Zhao, PhD

Joe Zhao, PhD

Alfred M. Shideler Professor of Pathology 
Director, Experimental Pathology 
Director, Pathology Graduate Program

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Rosemary Zuna, MD

Rosemary Zuna, MD

Section Head, Gynecologic Pathology

Professor of Pathology

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Adjunct Faculty

Charles Esmon, PhD

Charles Esmon, PhD

Lloyd Noble Chair, Cardiovascular Research

Member & Head, Cardiovascular Biology Research at OMRF

Adjunct Professor, Pathology

Adjunct Professor, Biochemistry

Investigator at Howard Hughes Medical Institute

Oklahoma Medical Research Foundation
825 N.E. 13th
Room A-205, Mail Box 45
Oklahoma City, Oklahoma 73104

405-271-6474

Charles-Esmon@omrf.ouhsc.edu

Education:

  • University of Illinois
    Urbana, Illinois
    B.S. - Chemistry (1969)
  • Washington University
    St. Louis, MO.
    Ph.D. - Biochemistry (1973)

Clinical/Research Interests:

My research focuses on the formation of blood clots and on the natural mechanisms that prevent these clots from forming inappropriately in blood vessels. When occlusive clots form within blood vessels, strokes, heart attacks, pulmonary emboli and phlebitis result. These processes are a major cause of death and morbidity. In a different disease process, bacterial or viral infection can lead to septic shock, a condition that is often associated with massive blood clotting especially in the small vessels. Once this process occurs, it is often fatal. We have identified components of the blood vessel that prevent these processes and are attempting to understand the relationship between these components and the above disease processes. Our studies are designed to identify how the components function and their potential utility in blocking these disease processes. These questions are addressed by biophysical methods including X-ray crystallography, biochemical, immunological, molecular biological and physiological studies. Preliminary clinical results support the concept that these agents may be safe and very effective in certain forms of vascular disease. Release of these components from the vessel wall can also be used as a monitor of blood vessel disease processes.

Select Honors & Accomplishments:

  • Member, National Academy of Sciences (2002- )

  • Inaugural Member, Oklahoma Inventors Hall of Fame (2002)

Select Publications:

  1. Rezale AR, HE X and Esmon CT. Thrombormodulin increases the rate of thrombin inhibition by BPTI. Biochemistry. 1998; 37: 693-699.

  2. Taylor FB Jr, Stearns-Kurosawa DJ, Kurowasa S, Ferrell G, Chang AC, Laszik Z, Kosanke S, Peer G and Esmon CT. The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis. Blood. 2000; 95:1680-1686.

  3. Gu JM, Fukudome K and Esmon CT. Characterization and regulation of the 5'-Flanking Region of the Murine Endothelial Protein C Receptor Gene. J Biol Chem. 2000; 275:12481-12488.

  4. Taylor FB Jr, Peer GT, Lockhart MS, Ferrell G, and Esmon CT.  EPCR plays an important role in protein C activation in vivo. Blood. 2001; 97:1685-1688.

  5. Safa O, Hensley K, Smirnov MD, Merrill JT, D'Angelo A, Esmon CT, and Esmon NL.  Lipid oxidation enhances the function of activated protein C and anti-phospholipid antibodies. J Biol Chem. 2001; 276:1829-1836.

  6. Oganesyan V, Oganesyan N, Terzyan S, Qu D, Dauter Z, Esmon NL, and Esmon CT.   The crystal structure of the endothelial protein C receptor and a bound phospholipid.  J Biol Chem. 2002 Jul 12;277(28):24851-4. Epub 2002 May 28.