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Internal Medicine

Mohammad Madhoun, MD, MS, FACP

​Associate Professor of Medicine
Chief, Section of Gastroenterology and Nutrition, Medicine Service (VA)
Director of Endoscopy (VA)
Site Director, GI Fellowship Program (VA)


COMD 7400
800 Stanton L Young Blvd
Oklahoma City, OK

405-271-5428 (Office)
405-271-5803 (Fax)

Dr. Mohammad Madhoun completed his medical degree at the Jordan University of Sciences and Technology in 2003, followed by the completion of an internship at the Princess Basma Hospital in Irbid, Jordan and a transitional residency year at the King Hussein Cancer Center in Amman, Jordan.   In 2005, he came to the University of Oklahoma Health Sciences Center to complete a residency program in Internal Medicine followed by a Gastroenterology fellowship. In 2011 upon his completion of the GI Fellowship Program, he was awarded the Richard F. Harty, M.D. Gastroenterology Fellow Award for Outstanding Fellow in Gastroenterology.  During his fellowship training, Dr. Madhoun also completed his Master of Science in Clinical Translational Sciences degree.

Dr. Madhoun is the local Site Director for the Gastroenterology Fellowship Program at the VA while also serving as a valuable member of the Program Evaluation and the Clinical Competency Committees.   In 2019, Dr. Madhoun was named as Program Liaison for the Gastroenterology Fellowship Program.  Since 2012-2020 Dr. Madhoun has been an active member of the Institutional Review Board for the College of Medicine, University of Oklahoma, serving as a member, Vice Chair and Chair.   On the national level he has served as an active member of the ASGE Research Committee since 2012, and in April 2020 he was named as the Chair of the ASGE Research Committee.  He has served on numerous committees at the VA, and due to his extraordinary efforts and accomplishments in clinical service, research, education and administration he was selected as the VA’s 2019 James F. Hammarsten Physician of Excellence Award honoree.  Due to his advocating for optimizing patient outcomes and his embodiment of the VA's I CARE core values of integrity, commitment, advocacy, respect and excellence, in January 2020 he was named as the Chief of the Section of Gastroenterology and Nutrition while also serving as the Director of Endoscopy at the VA.

Dr. Madhoun has a passion for teaching and has served as the Associate Director of the Gastroenterology and Hepatology Course for 1st year medical students at the University of Oklahoma Health Sciences Center since 2014.  He has been rewarded for his teaching efforts by being inducted into the Academy of Teaching Scholars in 2016 and in 2017 he was selected by his students to be presented with the prestigious Aesculapian Award for excellence in teaching.

Academic Section(s):

Digestive Diseases and Nutrition


Jordan University of Sciences and Technology
Irbid, Jordan
MD (2003)

Other Relevant Training

University of Oklahoma Health Sciences Center
MS, Clinical Translational Sciences (2011)

Board Certification(s):

2011 - Present  American Board of Gastroenterology

2008 - Present  American Board of Internal Medicine

2005 - Present  Oklahoma Medical Board



University of Oklahoma Health Sciences Center
Internal Medicine (2009)


University of Oklahoma Health Sciences Center
Gastroenterology (2011)


Clinical/Research Interests:

  • Diagnosis and early detection of liver cancer
  • Colorectal cancer screening


Clinical Trial Agreements

Madhoun, M. F. (Site PI), "A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Efficacy and Safety Study of SHP647 As Induction Therapy in Subjects with Moderate to Severe Ulcerative Colitis (FIGARO UC 302)," Sponsored by Shire Clinical Trial, Private
2018 - Present


Madhoun, M. F. (Co-Investigator), "Circulating Biomarkers for the Detection of Human Liver Diseases," Sponsored by VA MEDICAL CENTER OKC, Federal
October 1, 2018 - Present

Madhoun, M. F. (Co-Principal Investigator), "Colonoscopy versus Fecal Immunochemical Test in Reducing Mortality from Colorectal Cancer," Sponsored by VA Cooperative Studies Program #577, Federal Grant/Contract Number: #577
Total Direct Costs: $44,000,000.00
March 1, 2012 - June 30, 2024

Madhoun, M. F. (Principal Investigator), "Synchronized Intestinal Electrical Stimulation for Obesity," VA Merit Review Program, Sponsored by Department of Veternas Affairs, Federal
Total Direct Costs: $600,000.00
August 8, 2017 - September 30, 2019

Grants Completed

Madhoun, M. F. (Principal Investigator), "Efficacy and Tolerability of Various Bowel Preparations in Patients with Diabetes: A Radomized Controlled Trial," South Central VA Health Care Network (SCVAHCN) Research Grant, Sponsored by VA Health Services Research & Development (HSR&D), Federal
Total Direct Costs: $100,000.00
January 2015 - December 2017

Madhoun, M. F., Nusrat, S.*, "Use of Diphenhydramine as an Adjunctive Sedative for Colonoscopy in Patients Chronically on Opioids," Sponsored by American Society for Gastrointestinal Endoscopy - ASGE, Non-Profit
Total Direct Costs: $32,425.00
July 1, 2014 - June 30, 2016

Madhoun, M. F., "Cancer Stem Cell Markers in Hepatocellular Carcinoma," 2011 ACG "Smaller Programs" Clinical Research Award, Sponsored by American College of Gastroenterology, Non-Profit
Total Direct Costs: $16,497.00
July 1, 2011 - June 30, 2012

Select Honors & Accomplishments:

James F. Hammarsten VA Physician of Excellence Award, VA-OKC, 2019

American Society of Gastrointestinal Endoscopy Fellow, American Society of Gastrointestinal Endoscopy (ASGE), 2017 - Present

Aesculapian Award, University of Oklahoma Health Sciences Center and Tulsa SCM , 2017

Gastroenterology Fellow Teaching Award, Digestive Diseases and Nutrition, 2016

Inducted to the Academy of Teaching Scholars, University of Oklahoma Health Sciences Center, 2016

Gastroenterology Fellow Teaching Award, Digestive Diseases and Nutrition, 2015

Invited fellowship, American College of Physicians, 2015

Provost Research Award (Junior Faculty), College of Medicine, University of Oklahoma HSC (Nominated), 2015

Teaching Award for Research, Digestive Diseases and Nutrition, 2014

Quarterly Best Teaching Award, Digestive Diseases and Nutrition, 2012

Academic Honor Society, Phi Kappa Phi, Oklahoma Chapter, 2011

Clinical Forum Abstract, American Society of Gastrointestinal Endoscopy, 2011

Graduate Honor Society, Alpha Epsilon Lambda, Oklahoma Chapter, 2011

Richard F. Harty Award for Outstanding Fellow in Gastroenterology, Digestive Diseases and Nutrition, 2011

Twenty First Annual North American Conferences Gastroenterology Fellows (NACGF) selected research abstract, American College of Gastroenterology and Canadian Association of Gastroenterology, 2011

Who's Who in Medicine and Healthcare, Marquis, 2011

Clinical Plenary Abstract, American Society of Gastrointestinal Endoscopy, 2010

Fellowship2Leadership Gastroenterology/Hepatology Fellows' Travel Grant, Salix Fellow's Program, 2010

Fellow Travel Grant, American Gastrointestinal Association - Gastrointestinal Research Group, 2009

Distinguished Poster, American Association for the Study of Liver Diseases (Received), 2007

American Society of Internal Medicine Regional Associates Research Competition, Third Place, American College of Physicians, 2006


Select Publications:

Research Networking Profile

Zia, H. A.*, Madhoun, M. F. (2020). Cardiogenic Dysphagia by Dysphagia Megalatriensis & Aortica. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. PMID: 30404038. DOI: 10.1016/j.cgh.2018.10.049 Epub 2018 Nov 4 PMID: 30404038

Bitar H, Madhoun M, Tierney W. Response. Gastrointest Endosc. 2019 Feb; 89(2):446-447. doi:10.1016/j.gie2018.10.012. PMID.3066542

Bitar H, Madhoun M, Tierney W. Response. Gastrointest Endosc. 2018 Oct, 88(4): 781-782. doi.10.1016/j.gie2018.06.001.  PMID: 30217247

Madhoun, M. F., Chaudrey, K. K., Chisolm, S. S., Ahmed, A., Frost, B., Tierney, W. (2018). Efficacy and tolerability of various bowel preparations in diabetic patients: a randomized controlled tria. Endosc Int Open, 6(10), E1157-E1163. PMID: 30302371. DOI: 10.1055/a-0650-3908

Nusrat, S., Madhoun, M. F., Tierney, W. (2018). Use of Diphenhydramine as an adjunctive sedative for colonoscopy in patients on chronic opioid therapy: a randomized controlled trial. Gastrointestinal Endoscopy, 88(4), 695-702. PMID: 29689257. DOI: 10.1016/j.gie.2018.04.2342

Bitar, H.*, Zia, H.*, Bashir, M., Parava, P., Hanafi, M. Z.*, Tierney, W., Madhoun, M. F. (2018). Impact of Fellowship Training Level on Colonoscopy Quality and Efficiency Metrics. Gastrointestinal Endoscopy, 88(2), 378-387. PMID: 29679692. DOI: 10.1016/j.gie.2018.04.2338

Mahmood, S.*, Farooqui, S. M.*, Madhoun, M. F. (2018). Predictors of inadequate bowel preparation for colonoscopy: a systematic review and meta-analysis. European journal of gastroenterology & hepatology, 30(8), 819-826. PMID: 29847488. DOI: 10.1097/MEG.0000000000001175

Toschi, M. A.*, Saleem, G. A., Madhoun, M. F. (2018). Pseudomelanosis Duodeni in the Setting of Chronic Hydralazine Use. Am J Med Sci, 356(1), e21.

Madhoun, M. F., Bitar, H., Parava, P., Bashir, M. H., Zia, H. (2017). Patients with History of Colonoscopy Are Less Likely to Achieve High Quality Preparation After Implementing Split-Dose Bowel Preparation. Acta Gastro-enterologica, 80(2), 257-261. PMID: 29560691.

Bashir, M. H., Fazili, J., Madhoun, M. F., Kanagala, R., Chen, S., Nusrat, S. (2017). Impact of Sustained Virologic Response on Short-Term Clinical Outcomes in Hepatitis C-Related Cirrhosis. European Journal of Gastroenterology & Hepatology. PMID: 29200006. DOI: 10.1097/MEG.0000000000001032

Madhoun, M. F., Bitar, H., Bhatti, O., Zia, H., Parava, P., Bashir, M. H. (2017). Diabetics on Narcotics Are Less Likely to Achieve Excellent Bowel Preparation Than Are Patients with Either Condition. Digestive diseases and sciences, 62(3), 723-729. PMID: 28035547. DOI: 10.1007/s10620-016-4417-6

Kaitha SR, Salem G, Zhao YD, Madhoun MF, Chen A, Tierney WM. Response to Kane et al.  AM J Gastroenterol. 2017 Jun; 112(6):968-969; doi:10.1038/ajg.2017.103. PMID: 29572658

Associate Members

Zain Asad, MD

Zain Asad, MD

Assistant Professor

Guilherme Barreiro, MD, PhD

Guilherme Barreiro, MD, PhD

Assistant Professor of Surgery

Heather Burks, MD

Heather Burks, MD

Assistant Professor,
Obstetrics and Gynecology

Amanda Celii, MD

Amanda Celii, MD

Assistant Professor of Surgery

4th Year Surgery Clerkship Director

Associate Director, Trauma Post-Acute Care, EMS liaison

Associate Director, Trauma Outreach/Education

Stephen M. Clayton, Jr., MD

Stephen M. Clayton, Jr., MD

Assistant Professor

Kelley A. Curran, MD

Kelly A. Curran, MD

Associate Professor

M. Blake Evans, DO
Karl Huebner, M.D.

Karl Huebner, M.D.

Assistant Professor of Pediatrics

Jeremy Johnson, MD, FACS

Jeremy Johnson, MD, FACS

Assistant Professor of Surgery
Co-Director, Third Year Surgical Clerkship

Kellie R. Jones, MD, FCCP

Kellie R. Jones, MD, FCCP

Associate Professor, Medicine
Assistant Chief of Medicine, Oklahoma City VA Healthcare System
Fellow, American College of Chest Physicians

Edgar LeClaire, MD, MS, FACOG

Edgar LeClaire, MD, MS, FACOG

Assistant Professor

Fellowship Director

Amy Lee, M.D.

Amy Lee, M.D.

Associate Professor, Section of Pediatric Critical Care
Medical Director, Pediatric Intensive Care Unit
Program Director, Pediatric Critical Care Medicine Fellowship

Kathryn Lindsay, MD

Kathryn Lindsay, MD

Assistant Professor

Yashas Nathani, MD

Yashas Nathani, MD

Assistant Professor

Shashank S. Shettar, MD

Shashank S. Shettar, MD

Assistant Professor
Division Chief, Transplant Anesthesiology
Interim Division Chief, Obstetric Anesthesiology

Christine Vo, MD

Christine Vo, MD

Assistant Professor
Assistant Program Director
Medical Student Clerkship Co-Director

Houssein Youness, MD, FCCP

Houssein Youness, MD, FCCP

Associate Professor, Medicine
Interim Section Chief, Pulmonary, Critical Care & Sleep Medicine Section
Director of the Interventional Pulmonary Program, Oklahoma City VAHCS
Program Director, Pulmonary and Critical Care Fellowship, OUHSC
President, Oklahoma Thoracic Society
Fellow, American College of Chest Physicians