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Biochemistry and Physiology

Ann Louise Olson, PhD

Edith Kinney Gaylord Foundation and Presidential Associates Presidential Professor, Department of Biochemistry & Physiology

405-271-2227, x61252

Ann-Olson@ouhsc.edu


Education:

  • PhD in Human Nutrition from the University of Iowa, 1986


Clinical/Research Interests:

The central focus of my research is on insulin action and GLUT4-dependent glucose metabolism in adipose tissue.  GLUT4 is an important effector molecule for mediating the primary actions on insulin in these tissues.  Dysregulation of GLUT4 expression and its membrane trafficking plays a central role in mediating the abnormalities in intermediary metabolism and glucose homeostasis that are  associated with obesity and  lead to type 2 diabetes. 

Using transgenic mice to understand the complex regulation of the GLUT4 gene expression and GLUT4-dependent glucose metabolism has been important research tool.  Cell culture models are inadequate for understanding the complex physiologic milieu that exists in whole animals.  Recentlly, our focus has changed to understand how changes in glucose metabolism through the lifespan alter adipocyte regulation of whole body glucose homeostasis.


Select Publications:

Link to full publication list >



Associate Members

Zain Asad, MD

Zain Asad, MD

Assistant Professor
Associate Program Director, Cardiology Fellowship

Guilherme Barreiro, MD, PhD

Guilherme Barreiro, MD, PhD

Assistant Professor of Surgery
 

Heather Burks, MD

Heather Burks, MD

Associate Professor

Amanda Celii, MD

Amanda Celii, MD

Assistant Professor of Surgery

Associate Director, Trauma Post-Acute Care, EMS liaison

Associate Director, Trauma Outreach/Education

Stephen M. Clayton, Jr., MD

Stephen M. Clayton, Jr., MD

Assistant Professor

M. Blake Evans, DO

M. Blake Evans, DO

Assistant Professor

Laura Haws, M.D.

Laura Haws, M.D.

Fellowship Program Director,
Pediatric Critical Care
Assistant Professor of Pediatrics
Pediatric Critical Care Intensivist

Karl Huebner, M.D.

Karl Huebner, M.D.

Assistant Professor of Pediatrics
 

Jeremy Johnson, MD, FACS

Jeremy Johnson, MD, FACS

Assistant Professor of Surgery
Co-Director, Third Year Surgical Clerkship

Kellie R. Jones, MD, FCCP

Kellie R. Jones, MD, FCCP

Associate Professor, Medicine
Pulmonary, Critical Care & Sleep Medicine Section
Assistant Chief of Medicine, Oklahoma City VA Healthcare System
Director, Cystic Fibrosis Program
Fellow, American College of Chest Physicians

Alessandra Landmann MD

Alessandra Landmann, MD

Assistant Professor of Surgery

Fourth Year Surgery Clerkship Director 

Kathryn Lindsay, MD

Kathryn Lindsay, MD

Assistant Professor

Olivia Lust, DO

Olivia Lust, DO

Assistant Professor,
Associate Residency Program Director,
Residency Education Director,
Clinical Medicine Course Assistant Director

Yashas Nathani, MD

Yashas Nathani, MD

Assistant Professor

Assistant Medical Director, Pediatric Transport Team, Oklahoma Children's Hospital OU Health

George Salem, MD

George Salem, MD

Assistant Professor of Medicine
Director, Crohn’s and Colitis Center
OU Physicians, Edmond, OK

AGA TOP 25 Fellows 

Shashank S. Shettar, MD FASA

Shashank S. Shettar, MD, FASA

Assistant Professor

Associate Chief of Staff, Adult Services, OU Medical Center

Division Chief, Transplant Anesthesiology

Christine Vo, MD

Christine Vo, MD, FASA

Associate Professor
Medical Student Clerkship Director

Houssein Youness, MD, FCCP

Houssein Youness, MD, FCCP

Professor, Medicine
Section Chief, Pulmonary, Critical Care & Sleep Medicine Section
Director of the Interventional Pulmonary Program, Oklahoma City VAHCS
President, Oklahoma Thoracic Society
Fellow, American College of Chest Physicians