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Marisol Castillo-Castrejon, PhD
Pathology

Marisol Castillo-Castrejon, PhD

Assistant Professor
Section of Experimental Pathology
Harold Hamm Diabetes Center

marisol-castillocastrejon@ouhsc.edu

Dr. Marisol Castillo-Castrejon's research program envisions a life course approach and aims broadly to explore the role of nutrition on women’s health. Her research program is divided into three main areas: 1) placental function as a determinant of developmental programming of metabolic diseases ; 2) nutritional epidemiology & environmental exposures during pregnancy; and 3) menopause & diabetes risk.

Education:

  • BS- Nutrition and Food Sciences, Universidad Iberoamericana, Mexico City, Mexico (2000-2005)
  • MS - Summa Cum Laude, Experimental Biology, Universidad Nacional Autónoma de Mexico, Mexico City, Mexico (2006-2008)
  • PhD - Biological Sciences, Universidad Nacional Autónoma de México, Mexico City, Mexico (2009-2014)

Fellowship:

  • Epidemiology and Reproductive Toxicology - University of Michigan, Environmental Health Sciences Department (2014-2016)
  • Reproductive Sciences - Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus (2017-2020)

Clinical/Research Interests:

  • Developmental Origins of Health & Disease
  • Nutrition
  • Environmental Exposures
  • Menopause
  • Diabetes
  • Pregnancy
  • Placental  Function
  • Obesity
  • Adaptive Immunity
  • Women's Health

Funding:

  • Center for Advancement of Science & Technology, OCAST–HR23 (ranked #16/109)                      
  • Harold Hamm Foundation
  • Center for Indigenous Resilience, Culture, and Maternal Health Equity (CIRCLE) Pilot Grant
  • Cellular and Molecular GeroScience CoBRE
  • Oklahoma Shared Clinical and Translational Resources (OSCTR) Pilot Grant Program

Select Honors and Accomplishments:

  • President's Presenter's Award, Society for Reproductive Investigation (2024)
  • Trophoblast Research New Investigator Award, International Federation of Placenta Associations (IFPA) (2019)
  • Rebecca James Baker Memorial Prize, International Society of Environmental Epidemiology (2011)

Select Publications:

  1. Powell TL, Ferchaud-Roucher V, Madi L, Uhlson C, Zemski-Berry K, Kramer AC, Erickson K, Palmer C, Chassen SS, Castillo-Castrejon M. Synthesis of phospholipids in human placenta. Placenta. 2024 Mar 6;147:12-20. doi: 10.1016/j.placenta.2024.01.007. Epub 2024 Jan 21. PMID: 38278000; PMCID: PMC10923060.
  2. Castillo-Castrejon M, Yang IV, Davidson EJ, Borengasser SJ, Jambal P, Westcott J, Kemp JF, Garces A, Ali SA, Saleem S, Goldenberg RL, Figueroa L, Hambidge KM, Krebs NF, Powell TL. Preconceptional Lipid-Based Nutrient Supplementation in 2 Low-Resource Countries Results in Distinctly Different IGF-1/mTOR Placental Responses. J Nutr. 2021 Mar 11;151(3):556-569. doi: 10.1093/jn/nxaa354. PMID: 33382407; PMCID: PMC7948206.
  3. Castillo-Castrejon M, Yamaguchi K, Rodel RL, Erickson K, Kramer A, Hirsch NM, Rolloff K, Jansson T, Barbour LA, Powell TL. Effect of type 2 diabetes mellitus on placental expression and activity of nutrient transporters and their association with birth weight and neonatal adiposity. Mol Cell Endocrinol. 2021 Jul 15;532:111319. doi: 10.1016/j.mce.2021.111319. Epub 2021 May 12. PMID: 33989714; PMCID: PMC8206039.
  4. Ancira-Moreno M, O'Neill MS, Rivera-Dommarco JÁ, Batis C, Rodríguez Ramírez S, Sánchez BN, Castillo-Castrejón M, Vadillo-Ortega F. Dietary patterns and diet quality during pregnancy and low birthweight: The PRINCESA cohort. Matern Child Nutr. 2020 Jul;16(3):e12972. doi: 10.1111/mcn.12972. Epub 2020 Feb 9. PMID: 32037674; PMCID: PMC7296796.
  5. Buxton MA, Heydarzadeh S, Gronlund CJ, Castillo-Castrejon M, Godines-Enriquez MS, O'Neill MS, Vadillo-Ortega F. Associations between Air Pollution Exposure and Blood Pressure during Pregnancy among PRINCESA Cohort Participants. Toxics. 2023 May 3;11(5):424. doi: 10.3390/toxics11050424. PMID: 37235239; PMCID: PMC10222039