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Director of Lipidomics and Metabolomics Mass Spectrometry Facility

Director for the Lipidomics and Metabolomics Mass Spectrometry Laboratory

OUHSC is seeking an open-rank faculty member (non-tenure track) in the Department of Biochemistry and Physiology (https://medicine.ouhsc.edu/academic-departments/biochemistry-and-physiology) to serve as Director of the new OUHSC Lipidomics and Metabolomics Mass Spectrometry Laboratory. This is a unique opportunity to lead a new core facility that provides comprehensive biological mass spectrometry support for biomedical investigators using state-of-the-art instruments and technologies. Equipped with advanced LC/MS systems and the potential for additional instruments, this facility is poised to significantly enhance the capabilities of the core and provide cutting-edge research services to the scientific community.  The Director of this facility will provide scientific oversight, manage daily operations, develop novel methodologies, and collaborate closely with investigators to support cutting-edge research. This role specifically calls for a dynamic leader capable of maintaining high standards of technical excellence, recruiting additional technical expertise, and fostering a highly collaborative research environment as a member of the vibrant lipid research community at OUHSC and other institutions nationwide.

Education and Experience Requirements:

Ph.D. (preferred) or equivalent experience in bioanalytical chemistry, lipidomics, metabolomics or relevant subject area.

Main Responsibilities:

  • Scientific Oversight: Develop and maintain lipidomics and metabolomics workflows to conduct lipid and small metabolite analyses for investigators at OUHSC and other institutions (academic, government, and industry).
  • Facility Management: Oversee day-to-day operations, including supervising instruments, handling maintenance, and collaborating with technical staff by providing hands-on support in sample preparation, MS analyses, data acquisition, and analyses.
  • Method Development: Spear head the development of novel methods to address investigator needs, ensuring cutting-edge capabilities within the facility.
  • Investigator Collaboration: Partner with investigators in experimental design, sample preparation, data interpretation, and project support.
  • Data Communication: Deliver analyzed datasets (figures, text, data tables) to investigators and assist in writing manuscripts, presentations, and grant applications.
  • Training and Guidance: Provide technical training and problem-solving solutions to students, postdocs, and investigators conducting lipidomics and metabolomics experiments.
  • Fundraising and Advancement: Lead fundraising efforts to maintain state-of-the-art facilities, instrumentation, software, and data analysis pipelines.

Required Skills:

• Extensive experience in mass spectrometry, particularly in operating, maintaining, and troubleshooting nano-liquid chromatography-mass spectrometry systems.

• Proficiency in developing custom methods to meet specific investigator needs.

• Expertise in established lipidomics and metabolomics data analyses and bioinformatic tools.

• Strong skills in data management, interpretation and integration.

• Experience in developing business models for successful core facility operation.

• Experience with writing grant applications and maintaining core budgets and finances.

• Exceptional multi-tasking, time management and organizational skills.

 • Excellent verbal and written communication skills.

• Leadership qualities including honesty, integrity, flexibility, creativity, and a collaborative spirit.

• Ability to handle multiple projects and/or tasks in a fast-paced environment.

Desired Skills:

• Experience with imaging MS and/or multi-omic experiments and data set integration.

• Familiarity with establishing automated lab processes.

• Proficiency using commercial lipidomics software, including LIPID MAPs.

• Programming skills, particularly in R or Python.

Interested candidates should submit the following documents as a single PDF via email to: Ginnia Smith, Ginnia-Smith@ouhsc.edu

  • cover letter
  • curriculum vitae
  • two-page description of current and future research interests

For questions regarding these opportunities, please email: Ginnia-Smith@ouhsc.edu>

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