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Research

At the OU Department of Obstetrics and Gynecology, research starts with a simple question: how can we take better care of women tomorrow than we do today? Our physicians, scientists and trainees pursue that question everywhere it leads, from the lab bench to the bedside. We study the biology of gynecologic cancers, develop new treatments for infertility and PCOS, search for safer ways to care for mothers and babies, and advance surgery for pelvic floor disorders.

That work has made us one of the nation’s top OB/GYN departments for NIH funding, ranked 22nd in the country, with $16.9 million in research funding. In partnership with the NCI-designated Stephenson Cancer Center and collaborators across the country, we turn discoveries into clinical trials, and those trials into care that reaches patients across Oklahoma and beyond.

Areas of Focus

Gynecologic Oncology

Cancer trials and translational science

  • A leading accruer to NRG Oncology and GOG Partners trials, with phase I trialists on faculty
  • Investigator-initiated trials, including a Phase IB trial in advanced ovarian cancer
  • Route 66 Endometrial Cancer SPORE with Washington University and the University of New Mexico
  • DOD- and OCRA-funded research on DCLK1 in ovarian cancer

Maternal-Fetal Medicine

Pregnancy health and fetal programming

  • Research revenue up 500% since FY2016, reaching $2.2 million in external funding in FY2024.
  • Most funding from the NIH and other non-industry sources.
  • Basic science, translational studies, clinical trials and health services research.
  • 38+ peer-reviewed publications in the past five years

Reproductive Endocrinology & Infertility

Fertility, PCOS and reproductive aging

  • Natural supplements and new therapies for PCOS
  • AI analysis linking facial aging markers to ovarian reserve
  • Sperm lipids and male fertility outcomes
  • Sex hormones, immunity and metabolic change in menopause and PCOS

Urogynecology

Pelvic floor disorders and surgical innovation

  • National and international guidelines on preoperative imaging for prolapse
  • Multicenter trials of cell-based therapy for stress urinary incontinence
  • NIH-funded multicenter trial of simulation training for vaginal hysterectomy
  • Co-leading a multicenter study of vNOTES adnexectomy

General Obstetrics & Gynecology

Quality, education and everyday care

  • Statewide LARC training for primary care providers
  • A standardized birth plan for large group practices
  • Pain control for in-office gynecologic procedures
  • New treatments for HPV-related disease

Lactation

Breastfeeding policy and practice

  • Set the first national IBCLC hospital staffing guidelines
  • Lactation acuity tools adopted by hospitals nationwide
  • Research cited in the AAP’s 2022 breastfeeding policy statement
  • Supported Oklahoma Medicaid coverage of donor milk at home

Clinical Research

Learn about our current clinical trials in gynecologic cancer, fertility, pregnancy and general women’s health, and how to take part.

Clinical Research

Tiger Day Symposium

Our annual symposium where residents and fellows present their research to faculty and peers.

Visit Tiger Day

Contact Us

Department of Obstetrics and Gynecology

800 Stanton L. Young Blvd. Suite 2400
Oklahoma City, OK 73104
(405)271-8787