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Prabir K. Chakraborty, PhD

Prabir K. Chakraborty, PhD

Assistant Professor (Research)

Stephenson Cancer Center
975 N.E. 10th St
Oklahoma City, OK 73104

Education:

  • University of Calcutta
    Kolkata, India
    BS, Chemistry, 2000
  • University of Kalyani
    Kalyani, India
    MS, Biochemistry, 2002
  • Jadavpur University
    Kolkata, India,
    PhD - Biotechnology, 2009

Fellowship:

  • University of Florida
    Gainesville, FL
    Post-Doctoral Fellow 2013

Clinical/Research Interests:

  • Circadian Rhythm in Ovarian Cancer
  • Post translational modification by sulfhydration
  • Lipid metabolism pathways in ovarian cancer progression and chemoresistance

Select Publications:

  1. Chakraborty PK, Lee WK, Molitor M, Wolff NA, Thevenod F: Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells. Mol Cancer. 2010 May 8;9:102.

  2. Chakraborty PK, Scharner B, Jurasovic J, Messner B, Bernhard D, Thevenod F: Chronic cadmium exposure induces transcriptional activation of the Wnt pathway and upregulation of epithelial-to-mesenchymal transition markers in mouse kidney. Toxicol Lett. 2010 Sep 15; 198(1):69-76.

  3. Thevenod F, Chakraborty PK: The role of Wnt/beta-catenin signaling in renal carcinogenesis: lessons from cadmium toxicity studies. Curr Mole Med. 2010 Jun; 10(4):387-404. PMID: 20455852.

  4. Lee WK, Chakraborty PK, Roussa E, Wolff NA, Thevenod F: ERK1/2-dependent bestrophin-3 expression prevents ER-stress-induced cell death in renal epithelial cells by reducing CHOP. Biochim biophys Acta. 2012, 1823(10):1864-1876. PMID: 22705154.

  5. Lee WK, Chakraborty PK, Thevenod F: Pituitary homeobox 2 (PITX2) protects renal cancer cell lines against doxorubicin toxicity by transcriptional activation of the multidrug transporter ABCB1. Int J Cancer. 2013 Aug; 133(3):556-567. PMID: 23354914.

  6. Chakraborty PK, Zhang Y, Coomes AS, Kim WJ, Stupay R, Lynch LD, Atkinson T, Kim JI, Nie Z, Daaka Y: G Protein-Coupled Receptor Kinase GRK5 Phosphorylates Moesin and Regulates Metastasis in Prostate Cancer. Cancer Res. 2014 Jul; 74 (13): 3489–500. PMID: 24755472.