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Ram V. Roy, PhD
Pathology

Ram V. Roy, PhD

Assistant Professor of Research
Section of Experimental Pathology

940 Stanton L. Young Blvd
BMSB 451
Oklahoma City, OK 73104

Dr. Ram Roy's research focuses on understanding disease progression and the mechanisms involved in escaping chemotherapy.

Education:

  • BSc - Biochemistry, MPR Degree College, India (2000)
  • MSc - Biochemistry, Andhra University, India (2002)
  • MTech - BioTech, IIT-Kharagpur, India (2004)
  • PhD - Biological Science, NUS-Singapore, Singapore (2011)

Clinical/Research Interests:

  • Cancer Biology: Disease Progression Mechanism

Select Publications:

  1. Roy RV, Ardeshirylajimi A, Dinarvand P, Yang L, Rezaie AR. Occupancy of human EPCR by protein C induces β-arrestin-2 biased PAR1 signaling by both APC and thrombin. Blood. 2016 Oct 6;128(14):1884-1893. doi: 10.1182/blood-2016-06-720581. Epub 2016 Aug 25. PMID: 27561318; PMCID: PMC5054700.
  2. Xiong X, Rao G, Roy RV, Zhang Y, Means N, Dey A, Tsaliki M, Saha S, Bhattacharyya S, Dhar Dwivedi SK, Rao CV, McCormick DJ, Dhanasekaran D, Ding K, Gillies E, Zhang M, Yang D, Bhattacharya R, Mukherjee P. Ubiquitin-binding associated protein 2 regulates KRAS activation and macropinocytosis in pancreatic cancer. FASEB J. 2020 Sep;34(9):12024-12039. doi: 10.1096/fj.201902826RR. Epub 2020 Jul 21. PMID: 32692445; PMCID: PMC7808438.
  3. Roy RV, Means N, Rao G, Asfa S, Madka V, Dey A, Zhang Y, Choudhury M, Fung KM, Dhanasekaran DN, Friedman JE, Crawford HC, Rao CV, Bhattacharya R, Mukherjee P. Pancreatic Ubap2 deletion regulates glucose tolerance, inflammation, and protection from cerulein-induced pancreatitis. Cancer Lett. 2023 Dec 1;578:216455. doi: 10.1016/j.canlet.2023.216455. Epub 2023 Oct 19. PMID: 37865160; PMCID: PMC10897936.
  4. Rao G, Murphy B, Dey A, Dwivedi SKD, Zhang Y, Roy RV, Chakraborty P, Bhattacharya R, Mukherjee P. Cystathionine beta synthase regulates mitochondrial dynamics and function in endothelial cells. FASEB J. 2020 Jul;34(7):9372-9392. doi: 10.1096/fj.202000173R. Epub 2020 May 28. PMID: 32463541; PMCID: PMC7675787.
  5. Elechalawar CK, Rao G, Gulla SK, Patel MM, Frickenstein A, Means N, Roy RV, Tsiokas L, Asfa S, Panja P, Rao C, Wilhelm S, Bhattacharya R, Mukherjee P. Gold Nanoparticles Inhibit Macropinocytosis by Decreasing KRAS Activation. ACS Nano. 2023 May 23;17(10):9326-9337. doi: 10.1021/acsnano.3c00920. Epub 2023 May 2. Erratum in: ACS Nano. 2024 Mar 26;18(12):9242. doi: 10.1021/acsnano.4c01293. PMID: 37129853; PMCID: PMC10718652.