Dr. Nagykáldi is a Professor and Director of Research in the Department of Family and Preventive Medicine at the University of Oklahoma Health Sciences Center. He is also the Research Director of the Oklahoma Physicians Resource / Research Network (OKPRN), the Associate Director of Community-Engaged Research within the Oklahoma Shared Clinical and Translational Resource (OSCTR) and the Associate Director of the Oklahoma Primary Healthcare Improvement Collaborative (OPHIC). He holds a Bachelor’s degree in pharmacy and a PhD in pharmacology with training in public health and epidemiology as well as a Bachelor’s degree in Theology.
Since 2001, Dr. Nagykaldi has been working closely with healthcare professionals and tribal, rural, and underserved community stakeholders throughout the United States and internationally to improve the quality, safety, cost, and experience of healthcare through practice-based and community-engaged health services research and implementation and dissemination (D&I) science. He participated in or led over 30 research and quality improvement projects that focused on preventive services delivery, management of chronic conditions, patient and community-centered healthcare, clinical decision support, shared decision making, and the development or implementation of health information technology in primary care settings. Partnering with patients and clinicians, he developed over 20 technology applications that helped improve patient care in Oklahoma and nationally. He also facilitated the development of public-private partnerships, primary care pandemic preparedness, practice facilitation, and community-engaged, participatory research. Dr. Nagykáldi authored over 70 peer-reviewed publications and presented widely on his work. He has also taught and mentored numerous undergraduate and graduate students with various healthcare backgrounds.
Academic Section(s):
OUFMC Research Division
Education:
- Semmelweis University of Medicine, Budapest, Hungary - Bachelor's in Pharmacy (1996)
- University of Oklahoma College of Medicine - Predoctoral Fellowship (1997 - 1999)
- Semmelweis University of Medicine, Budapest, Hungary - PhD in Pharmacology (2000)
- University of Oklahoma HSC, Heart Rhythm Institute - Postdoctoral Fellowship (2000 - 2001)
- OUHSC Department of Family Medicine - K08 Training in epi/bio and health services research (2008 - 2013)
- Newman University, Wichita, Kansas - Bachelor's in Theology (2021)
Clinical/Research Interests:
- Practice-based, translational health services research
- Community-engaged research (CEnR)
- Implementation and dissemination (D&I) science
- Health information technology R&D and implementation
- Primary care practice facilitation and practice redesign
- Patient-centered and goal-oriented healthcare
- Shared decision making
- Technology-assisted risk assessment and health planning
- Preventive services screening and delivery
- Chronic disease management
Funding:
RECENT RESEARCH PROJECTS
Oklahoma Tribal, Rural, Urban Cancer Screening Trial ACCESS Hub
UG1CA287044, Doescher/Moore (PIs) 12/01/2023 – 11/30/2027
National Cancer Institute (NCI) $4,315,560
The overarching goal for the Stephenson Cancer Center (SCC) Oklahoma Tribal, Rural, Urban Cancer Screening Trial (OK TRUST) ACCESS Hub is to enhance capacity for increasing cancer screening trials accrual and participation among tribal, rural and urban populations across Oklahoma.
Addressing Opioid Use Disorder in Older Adults through Primary Care Innovation (OUD-PCI)
1R18HS027913-01, Nagykaldi (Co-PI) 10/01/2020 – 09/29/2024
Agency for Healthcare Research and Quality (AHRQ) $2,499,995
Patients who are older or suffer from conditions that cause chronic pain that interferes with their lives are at considerably higher risk for adverse effects of opioid medications. Therefore, addressing the specific needs
and health challenges of these populations through innovative pain management strategies that can be implemented in primary care settings is urgently needed. To address these needs, our team designed a multifaceted, person-centered and scalable program that can be implemented in primary care practices and which aims at improving pain management for older adults and those with functional disabilities or increased social risk.
Tribally Engaged Approaches to Lung Screening (TEALS Trial)
1R01CA225439-01A1, Nagykaldi (PI) 04/01/2019 – 11/30/2024
National Cancer Institute (NCI) $2,361,468
Over the course of 5 years, TEALS will: 1) Conduct focus groups and semi-structured interviews with CNHSA patients, clinicians, and health administrators to elucidate individual- and system-level barriers and facilitators that affect the implementation of LCS; 2) Develop, and iteratively refine an LCS care coordination intervention that will identify eligible persons for LCS, help these patients navigate the screening process, and link them with smoking cessation services, when applicable; 3) Measure the impact of the TEALS intervention on the receipt of screening and a set of patient- and practice-level outcomes by conducting a cluster-randomized clinical trial of LCS implementation; and 4) Disseminate the TEALS program to other researchers and healthcare systems that serve AI/AN patients.
International Conference on Practice Facilitation 2020, 2021, 2022
1 R13 HS027287-01, Nagykaldi (PI) 09/30/2020 – 09/29/2023
Agency for Healthcare Research and Quality (AHRQ) $123,867
The Steering Committee of the International Conference on Practice Facilitation (ICPF), working with the North American Primacy Care Research Group (NAPCRG) and other collaborators will develop and organize annual conferences to be held in 2021, 2022, and 2023. The ICPF conference will: 1) Expand and further develop the current annual conference, responding to the emerging and growing professional needs of PFs worldwide; 2) Establish a maintainable approach to develop and grow the ongoing PF Learning Community; and 3) Leveraging the PF Learning Community structure, guide the activities of ICPF toward the establishment of an International Society for Practice Facilitation that will spearhead the strategic professional development of PFs.
Expansion and Enhancement of Medical School Curriculum to Increase Physician Workforce in Underserved Oklahoma Communities
1 T99HP335580100, Herman/Crawford (PIs) 09/01/2019 – 08/31/2023
Health Resources and Services Administration (HRSA) $4,704,476
The University of Oklahoma College of Medicine (OU) is submitting an “Expansion and Enhancement of Medical School Curriculum to Increase Physicians in Underserved Oklahoma Sites” to create the Primary Care Pathways to Sustainable Health and Healthcare Network. OU aims to develop this Primary Care Pathways Network to identify and mentor students from tribal, rural, and medically underserved communities in Oklahoma (TRU-OK) beginning K-12 through medical school.
Role: Co-Investigator
Institutional Development Award (IDeA) Program Infrastructure for Clinical and Translational Research
1U54RR033563, James (PI/OUHSC) 08/01/2018 – 07/31/2023
NIH $1,496,350
We propose to strengthen productive bidirectional relationships between researchers and communities in Oklahoma with an emphasis on primary care clinicians, pharmacists, and American Indian communities, expand community test sites by enhancing three practice-based research networks and build a system-wide dissemination/implementation/diffusion infrastructure consisting of county health improvement organizations (CHIOs) linked to each other and, through regional coordinating centers, to the academic research partners.
Role: Co-Investigator
Addressing Health Disparities among Oklahoma Minority and Rural Communities through Clinical Research Education and Career Development
1R25MD011564-01, Stoner/Houchen (Co-PIs) 09/24/2017 – 05/31/2022
National Institutes of Health (NIH/NIMHD) $499,072
The overall goal of this research education and career development program is to enhance clinical research methods expertise and research careers among underrepresented researchers focused on health disparities and minority health.
Role: Senior Mentor and Course Instructor
Testing the Effectiveness of Individualized Disease Prevention for Middle-Aged Adults
R01AG059979, Taksler (PI, Cleveland Clinic) 04/01/2019 – 03/31/2024
National Institute on Aging (NIA) $497,878
This project will help middle-aged adults to make an informed decision about the health care services that are most likely to promote a longer, healthier life. We will adapt a previously-published analytic model to incorporate quality of life and integrate a previously-developed decision aid into electronic health records. Then, in a randomized trial at diverse primary care clinics, we will test of effectiveness of the decision aid on preventive care utilization for middle-aged patients.
Role: Co-Investigator
CCSG – supplemental #2 – Building Cancer Survivorship Research Capacity in Rural Oklahoma
3P30CA225520-01S1, Mannel (PI) 05/01/2019 – 04/30/2022
National Cancer Institute (NCI) $96,469
Use community-engagement processes to co-design a tailored cancer care coordination system featuring nurse rural cancer care coordinators (RC3s) embedded within rural healthcare delivery systems who will help improve ONC-PCP communications. Test preliminary effectiveness of the RC3 implementation by examining processes and outcomes using a quasi-experimental design with patient- and system-level care coordination measures collected before and after implementation in at least 30 CNHSA and 30 WCWI patients. Identify factors that facilitate or hinder RC3 effectiveness.
Role: Co-Investigator
CCSG – supplemental #2 – Colorectal Cancer Screening Implementation in Partnership with Native American Communities
3P30CA225520-01S2, Mannel (PI) 05/01/2019 – 04/30/2022
National Cancer Institute (NCI) $224,082
The overall objective of the two-phased project is to increase CRC screening uptake in AIs aged 50 to 75 years who are at average risk for CRC. For this purpose, we will test the effectiveness of a comprehensive, multilevel (i.e., individual, community, and systems/ organizational), and multi-component (i.e., small media, navigation services) intervention with AI populations (on and off tribal lands) across the three states. We will focus on culturally appropriate evidence-based strategies that promote any guideline approved CRC screening (i.e., fecal immunochemical test, colonoscopy, computed tomographic colonography). During the planning phase (Year 1, eight months), we will build community-academic partnerships between I/T/U healthcare facilities, tribal entities, and university-based cancer centers; and secure tribal authorizations, IRB approvals and data sharing agreements. We will also adapt and pilot test the intervention processes and strategies. During the implementation phase (Years 2-5), we will test dissemination and implementation of multilevel and multi-component evidence-based strategies for enhancing screening. We will finalize these strategies after participatory input from our three state-specific Community Advisory Committees. Findings from this research could lead to an immediate increase in CRC screening and ultimately enhance cancer health equity by reducing the preventable CRC disease burden among AIs.
Role: Co-Investigator