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Suresh Niture, PhD
Radiation Oncology

Suresh Niture, PhD

Staff Scientist 

Department of Radiation Oncology 

Office  

Stephenson Cancer Center 

800 NE 10th Street - Suite L100 

Oklahoma City, OK 73104

405/271-3016

suryakant-niture@ouhsc.edu

Education:

PhD, University of Pune (NCL-CSIR), Pune, India, 2003

Postdoctoral Training, Texas Tech University, Amarillo, TX USA 2004-2007

Research Associate/Scientist, UM Baltimore-MD & NCCU Durham-NC USA 2008-2024

Clinical/Research Interests:

In our laboratory, we are currently investigating how radiation therapy modulates oncogenic and immune signaling that affects breast cancer and its tumor microenvironment (TEM) specifically in highly aggressive and metastatic triple-negative breast cancer (TNBC).  To explore the radiation impact on breast cancer tumor biology, we are using breast cancer tumor cell lines, animal models, and patient-derived tumor and blood samples. We will examine and analyze the potential molecular mechanisms that cause radio-resistance in breast cancer and design an effective adjuvant therapeutic approach to control these cancers.

Select Publications:

  1. Niture S, Mooers BHM, Wu DH, Hart M, Jaboin J, Seneviratne D.  Dual-specificity protein phosphatase 1 (DUSP1/MKP1): A Potential Therapeutic Target in Cancer, iScience IN PRESS.
  2. Niture S, Ghosh S, Jaboin J, Seneviratne D. Tumor Microenvironment Dynamics of Triple-Negative Breast Cancer Under Radiation Therapy. Int J Mol Sci. 2025 Mar 20;26(6):2795. doi: 10.3390/ijms26062795. PMID: 40141437.
  3. Ofosu-Boateng M, Choi S, Kim S, Twum E, Nnamani DO, Gebreyesus LH, Niture S, Yadak N, Kumar D, Gonzalez FJ, Liangpunsakul S, Cui JY, Gyamfi MA. Human PXR Signaling Exacerbates Ethanol-Induced Liver Injury in Females: Evidence from Mouse Models and Human ALD Cohorts. Cell Mol Gastroenterol Hepatol. 2025 Jul 16:101589. doi: 10.1016/j.jcmgh.2025.101589.  PMID: 40681042.
  4. Obu S, Niture S, Hoang H, Gadi S, Vandana, He Y, Kumar D. Clemastine and hyperthermia enhance sensitization of osteosarcoma cells for apoptosis. Mol Cell Oncol. 2024, 14;11(1):2351622. doi: 10.1080/23723556.2024.2351622. PMID: 38778919;
  5. Niture S, Gadi S, Qi Q, Gyamfi MA, Varghese RS, Rios-Colon L, Chimeh U, Vandana, Ressom HW, Kumar D. MicroRNA-483-5p Inhibits Hepatocellular Carcinoma Cell Proliferation, Cell Steatosis, and Fibrosis by Targeting PPARα and TIMP2. Cancers (Basel). 2023 Mar 10;15(6):1715. doi: 10.3390/cancers15061715. PMID: 36980601.
  6. Niture S, Gyamfi MA, Lin M, Chimeh U, Dong X, Zheng W, Moore J, Kumar D. TNFAIP8 regulates autophagy, cell steatosis, and promotes hepatocellular carcinoma cell proliferation. Cell Death Dis. 2020 Mar 9;11(3):178. doi: 10.1038/s41419-020-2369-4. PMID: 32152268.
  7. Niture S, Gyamfi MA, Kedir H, Arthur E, Ressom H, Deep G, Kumar D. Serotonin induced hepatic steatosis is associated with modulation of autophagy and notch signaling pathway. Cell Commun Signal. 2018 Nov 8;16(1):78. doi: 10.1186/s12964-018-0282-6. PMID: 30409162.
  8. Niture S, Ramalinga M, Kedir H, Patacsil D, Niture SS, Li J, Mani H, Suy S, Collins S, Kumar D. TNFAIP8 promotes prostate cancer cell survival by inducing autophagy. Oncotarget. 2018 Jun 1;9(42):26884-26899. doi: 10.18632/oncotarget.25529. PMID: 29928491.