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Faculty

The Infectious Diseases Section is comprised of nationally known faculty committed to providing the highest quality education, research, and patient care possible.
Joseph Sassine, MD
Internal Medicine

Joseph Sassine, MD

Assistant Professor of Medicine
Associate Director, Infectious Diseases Fellowship Program

Subspecialty - Transplant Infectious Diseases

800 Stanton L. Young Blvd.
AAT 7300
Oklahoma City, OK  73104

405-271-6122

joseph-sassine@ouhsc.edu

Dr. Sassine received his medical degree from the Lebanese American University School of Medicine in Lebanon. He subsequently completed a residency in Internal Medicine at the Icahn School of Medicine at Mount Sinai, St. Luke’s-Roosevelt Hospital Center in New York, NY, where he also served as a Chief Resident. He subsequently pursued a fellowship in Infectious Diseases, Immunocompromised Track, at the University of Texas Health Science Center and MD Anderson Cancer Center in Houston, TX, where he also served as a Chief Fellow. He is currently an Assistant Professor of Medicine at the Infectious Diseases Section in the University of Oklahoma Health Sciences Center.

He specializes in diagnosing and treating infections in immunocompromised hosts, including transplant recipients and patients with cancer. His research interests include infections in patients with hematological malignancies, including hematopoietic cell transplantation and CAR T cell recipient.

Academic Section(s):

Infectious Diseases

Education:

Medical School – MD: Lebanese American University School of Medicine, Byblos, Lebanon

Board Certification(s):

  • Internal Medicine
  • Infectious Diseases

Residency:

Internal Medicine: Icahn School of Medicine at Mount Sinai, St. Luke’s-Roosevelt Hospital Center, New York, NY

Fellowship:

Infectious Diseases: University of Texas Health Science Center and MD Anderson Cancer Center, Houston, TX

Memberships:

American College of Physicians

Infectious Diseases Society of America

American Society of Transplantation 

American Society of Transplantation and Cellular Therapy.

Clinical/Research Interests:

  • Infections in transplant recipients
  • Infections in patients with cancer

Select Publications:

Siegrist, E. A., Sassine, J. (2022). Antivirals with Activity Against Monkeypox: A Clinically Oriented Review. Clinical Infectious Diseases. PMID: 35904001. DOI: 10.1093/cid/ciac622

Siegrist, E. A., Sassine, J. (2022). Shorter might not always be better: the case for longer antibiotic therapy for Pseudomonas aeruginosa pneumonia. Intensive Care Medicine, 48(7), 963-964. PMID: 35616656. DOI: https://doi.org/10.1007/s00134-022-06754-6

Khawaja, F., Sassine, J., Handley, G., Iyer, S. P., Ramdial, J., Ahmed, S., Nieto, Y., Spallone, A., Ariza-Heredia, E. J., Chemaly, R. F. (2022). Herpesviruses Infections in CAR T Cell Recipients. Transplantation and Cellular Therapy, 28(3), S381-S382.

Farkas, A., Oikonomou, K., Ghanbar, M., Villasurda, P., Varghese, J., Lipman, J., Sassine, J., Ranganathan, D., Roberts, J. A. (2022). Population Pharmacokinetics of Intraperitoneal Gentamicin and the Impact of Varying Dwell Times on Pharmacodynamic Target Attainment in Patients with Acute Peritonitis Undergoing Peritoneal Dialysis. Antimicrobial Agents and Chemotherapy, 66(2), e01679-21.

Spallone, A., Srinivasan, K., Sassine, J., Shigle, T. L., Handy, V., Ramdial, J., Khawaja, F., Ariza Heredia, E., Chemaly, R. F. (2021). 922. The Impact of Clinically Significant CMV Infections on Other Viral Infections in the Era of Letermovir Primary Prophylaxis. Open Forum Infectious Diseases, 8(Supplement 1), S552-S553.

Sassine, J., Khawaja, F., Shank, B. R., Lovell, A., Lee, J., DiPippo, A., Rausch, C. R., Spallone, A., Ariza Heredia, E., Chemaly, R. F. (2021). 930. Clinically Significant CMV Infections in Patients with Lymphoma or Multiple Myeloma. Open Forum Infectious Diseases, 8(Supplement 1), S557-S558.

Sassine, J., Kontoyiannis, D. P. (2021). A 77-Year-Old Man with Multiple Myeloma and a Lytic Bone Lesion. Am J Med, 134(7), 860-862. PMID: 33621531. DOI: 10.1016/j.amjmed.2021.01.032

Sassine, J., Khawaja, F., Shigle, T. L., Handy, V., Foolad, F., Aitken, S. L., Jiang, Y., Champlin, R., Shpall, E., Rezvani, K., Ariza-Heredia, E., Chemaly, R. F. (2021). Refractory and Resistant Cytomegalovirus after Hematopoietic Cell Transplant in the Letermovir Primary Prophylaxis Era. Clinical Infectious Diseases, 73(8), 1346-1354. PMID: 33830182. DOI: 10.1093/cid/ciab298

Sassine, J., Khawaja, F., Shank, B. R., Lovell, A., Lee, J., DiPippo, A., Rausch, C., Chemaly, R. F. (2021). Letermovir Use in Patients with Relapsed or Refractory Hematological Malignancies. Transplant Cell Ther, 27(3), S346-S348.

Malek, A. E., Adachi, J. A., Mulanovich, V. E., Sassine, J., Raad, I. I., McConn, K., Seiler, G. T., Dhal, U., Khawaja, F., Chemaly, R. F. (2021). Immune reconstitution and severity of COVID-19 among hematopoietic cell transplant recipients. Transplant Infectious Diseases, 23(4), e13606. PMID: 33755273. DOI: 10.1111/tid.13606

Khawaja, F., Mullane, K., El Haddad, L., Sassine, J., Ariza-Heredia, E., Tang, Y., Raval, A. D., Chemaly, R. F. (2020). 568. Healthcare Cost and Length of Stay for Cytomegalovirus (CMV) Infection-Related Hospitalizations in Allogeneic Hematopoietic Cell Transplant (allo-HCT) Recipients: A Multicenter Analysis. Open Forum Infect Dis, 7(Suppl 1), S348-S349.

Sassine, J., Khawaja, F., Handy, V., Shigle, T. L., Foolad, F., Aitken, S. L., Ariza-Heredia, E., Chemaly, R. F. (2020). 580. Refractory and Resistant CMV Infections in Hematopoietic Cell Transplant Recipients in the Letermovir Primary Prophylaxis Era. Open Forum Infect Dis, 7(Suppl 1), S355.

Farkas, A., Sassine, J., Mathew, J., Stavropoulos, C., Stern, R., Mckinley, G. (2018). Outcomes associated with the use of a revised risk assessment strategy to predict antibiotic resistance in community-onset pneumonia: a stewardship perspective. J Antimicrob Chemother, 73(9), 2555-2558. PMID: 29897465. DOI: 10.1093/jac/dky202