The history of plastic surgery is closely aligned with the development of oncologic surgery. The Plastic Surgeons at OU are trained in both primary management of advanced cutaneous (skin) malignancies, including melanoma, and the reconstruction of defects created by the removal of such cancers. The Chief of Plastic Surgery at OU, Dr. Anthony P. Tufaro, has been trained in surgical oncology with a specialty in head and neck cancer. The management of these complicated problems, including tumors of the mouth, tongue, salivary glands, jaw, skull base, thyroid, and parathyroid glands, requires a multidisciplinary approach to accomplish the best outcomes. This requires state-of-the-art care of the primary tumor and reconstruction of the hard and soft tissues to return patients to a functional cancer-free life.