Academic Section(s):
Rheumatology, Immunology, Allergy
Education:
- MSc in Clinical and Translational Science, University of Alabama at Birmingham, Birmingham AL (2019)
- Doctor of Medicine, University of Sao Paulo, Brazil (2004)
Residency:
Internal Medicine Residency, Cleveland Clinic Foundation, Cleveland, OH (2008)
Fellowship:
Rheumatology Fellowship, Columbia University, New York, NY (2010)
Clinical/Research Interests:
- Effects of obesity on disease activity of patients with rheumatoid arthritis: mechanisms and nutritional interventions
- Physical impairment in rheumatoid arthritis and exercise interventions
- Skeletal muscle dysfunction
- Changes in body composition
- Insulin resistance
- Cardiovascular disease
- Idiopathic inflammatory myopathies
Select Publications:
Moellering DR, Smith-Johnston K, Kelley C, Sammy MJ, Benedict J, Brock G, Johnson J, Baskin KK, Jarjour WN, Belury MA, Reiser PJ, Nagareddy PR, Hanaoka BY. Association between skeletal muscle mitochondrial dysfunction and insulin resistance in patients with rheumatoid arthritis: a case-control study. Arthritis Res Ther. 2023 May 20;25(1):85. doi: 10.1186/s13075-023-03065-z. PubMed PMID: 37210569; PubMed Central PMCID: PMC10199606.
Dragoljevic D, Lee MKS, Pernes G, Morgan PK, Louis C, Shihata W, Huynh K, Kochetkova AA, Bell PW, Mellett NA, Meikle PJ, Lancaster GI, Kraakman MJ, Nagareddy PR, Hanaoka BY, Wicks IP, Murphy AJ. Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis. Clin Transl Immunology. 2023;12(4):e1446. doi: 10.1002/cti2.1446. eCollection 2023. PubMed PMID: 37091327; PubMed Central PMCID: PMC10113696.
Dahdah A, Johnson J, Gopalkrishna S, Jaggers RM, Webb D, Murphy AJ, Hanssen NMJ, Hanaoka BY, Nagareddy PR. Neutrophil Migratory Patterns: Implications for Cardiovascular Disease. Front Cell Dev Biol. 2022;10:795784. doi: 10.3389/fcell.2022.795784. eCollection 2022. Review. PubMed PMID: 35309915; PubMed Central PMCID: PMC8924299.
Hanaoka BY, Zhao J, Heitman K, Khan F, Jarjour W, Volek J, Brock G, Gower BA. Interaction effect of systemic inflammation and modifiable rheumatoid cachexia risk factors on resting energy expenditure in patients with rheumatoid arthritis. JCSM Clin Rep. 2022 Jan;7(1):12-23. doi: 10.1002/crt2.45. Epub 2022 Jan 7. PubMed PMID: 38288252; PubMed Central PMCID: PMC10824535.
Dragoljevic D, Lee MKS, Louis C, Shihata W, Kraakman MJ, Hansen J, Masters SL, Hanaoka BY, Nagareddy PR, Lancaster GI, Wicks IP, Murphy AJ. Inhibition of interleukin-1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis. Clin Transl Immunology. 2020;9(11):e1206. doi: 10.1002/cti2.1206. eCollection 2020. PubMed PMID: 33204425; PubMed Central PMCID: PMC7652637.
Coleman KJ, Schlundt DG, Bonnet KR, Holmquist KJ, Dunne J, Crull E, Hanaoka BY, Lent MR, Nadglowski J, Sylvia LG, Venkatachalam S, Xanthakos SA, Zeiger R, Arterburn D, Williams N, Courcoulas A, Anau J, McTigue KM. Correction to: Understanding the Bariatric Patient Perspective in the National Patient-Centered Clinical Research Network (PCORnet) Bariatric Study. Obes Surg. 2020 May;30(5):1848. doi: 10.1007/s11695-020-04475-7. PubMed PMID: 32064555.
Coleman KJ, Schlundt DG, Bonnet KR, Holmquist KJ, Dunne J, Crull E, Hanaoka BY, Lent MR, Nadglowski J, Sylvia L, Venkatachalam S, Xanthakos SA, Zeiger R, Arterburn D, Williams N, Courcoulas A, Anau J, McTigue KM, Blalock C, Malanga E, McClay J, McBride CL, Schlundt D, Emiliano A, Nemr R, McTigue K, Courcoulas A, Xanthakos SA, Michalsky M, Coleman KJ, Murali S, Tavakkoli A, Desai N, Apovian C, Clark J, Nauman E, Cirielli E, Nadglowski J, St Clair T, Tice J, Vitello J, Zeiger R, Arterburn D, Anau J, Janning C, Williams N. Understanding the Bariatric Patient Perspective in the National Patient-Centered Clinical Research Network (PCORnet) Bariatric Study. Obes Surg. 2020 May;30(5):1837-1847. doi: 10.1007/s11695-020-04404-8. PubMed PMID: 31965490.
Sreejit G, Abdel-Latif A, Athmanathan B, Annabathula R, Dhyani A, Noothi SK, Quaife-Ryan GA, Al-Sharea A, Pernes G, Dragoljevic D, Lal H, Schroder K, Hanaoka BY, Raman C, Grant MB, Hudson JE, Smyth SS, Porrello ER, Murphy AJ, Nagareddy PR. Neutrophil-Derived S100A8/A9 Amplify Granulopoiesis After Myocardial Infarction. Circulation. 2020 Mar 31;141(13):1080-1094. doi: 10.1161/CIRCULATIONAHA.119.043833. Epub 2020 Jan 16. PubMed PMID: 31941367; PubMed Central PMCID: PMC7122461.
Hanaoka BY, Ithurburn MP, Rigsbee CA, Bridges SL Jr, Moellering DR, Gower B, Bamman M. Chronic Inflammation in Rheumatoid Arthritis and Mediators of Skeletal Muscle Pathology and Physical Impairment: A Review. Arthritis Care Res (Hoboken). 2019 Feb;71(2):173-177. doi: 10.1002/acr.23775. Epub 2019 Jan 4. Review. PubMed PMID: 30295435; PubMed Central PMCID: PMC6353677.
Dragoljevic D, Kraakman MJ, Nagareddy PR, Ngo D, Shihata W, Kammoun HL, Whillas A, Lee MKS, Al-Sharea A, Pernes G, Flynn MC, Lancaster GI, Febbraio MA, Chin-Dusting J, Hanaoka BY, Wicks IP, Murphy AJ. Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis. Eur Heart J. 2018 Jun 14;39(23):2158-2167. doi: 10.1093/eurheartj/ehy119. PubMed PMID: 29905812; PubMed Central PMCID: PMC6001889.
Hanaoka BY, Ormseth MJ, Michael Stein C, Banerjee D, Nikolova-Karakashian M, Crofford LJ. Secretory sphingomyelinase (S-SMase) activity is elevated in patients with rheumatoid arthritis. Clin Rheumatol. 2018 May;37(5):1395-1399. doi: 10.1007/s10067-017-3824-1. Epub 2017 Sep 15. PubMed PMID: 28914380; PubMed Central PMCID: PMC6050169.
Hanaoka BY, Cleary LC, Long DE, Srinivas A, Jenkins KA, Bush HM, Starnes CP, Rutledge M, Duan J, Fan Q, Fraser N, Crofford LJ. Physical impairment in patients with idiopathic inflammatory myopathies is associated with the American College of Rheumatology functional status measure. Clin Rheumatol. 2015 Nov;34(11):1929-37. doi: 10.1007/s10067-014-2821-x. Epub 2014 Nov 12. PubMed PMID: 25388646; PubMed Central PMCID: PMC5244815.
Cleary LC, Crofford LJ, Long D, Charnigo R, Clasey J, Beaman F, Jenkins KA, Fraser N, Srinivas A, Dhaon N, Hanaoka BY. Does computed tomography-based muscle density predict muscle function and health-related quality of life in patients with idiopathic inflammatory myopathies?. Arthritis Care Res (Hoboken). 2015 Jul;67(7):1031-40. doi: 10.1002/acr.22557. PubMed PMID: 25623494; PubMed Central PMCID: PMC5207482.
Hanaoka BY, Peterson CA, Crofford LJ. Glucocorticoid effects on skeletal muscle: benefit and risk in patients with autoimmune inflammatory rheumatoid diseases. Expert Rev Clin Immunol. 2012 Nov;8(8):695-7. doi: 10.1586/eci.12.76. PubMed PMID: 23167679.
Hanaoka BY, Peterson CA, Horbinski C, Crofford LJ. Implications of glucocorticoid therapy in idiopathic inflammatory myopathies. Nat Rev Rheumatol. 2012 Aug;8(8):448-57. doi: 10.1038/nrrheum.2012.85. Epub 2012 Jun 12. Review. PubMed PMID: 22688888.
Hanaoka BY, Libecco J, Rensel M, Hajj-Ali RA. Peripheral mononeuropathy with etanercept use: case report. J Rheumatol. 2008 Jan;35(1):182. PubMed PMID: 18176996.
de Carvalho JF, Hanaoka B, Szyper-Kravitz M, Shoenfeld Y. C-Reactive protein and its implications in systemic lupus erythematosus. Acta Reumatol Port. 2007 Oct-Dec;32(4):317-22. Review. PubMed PMID: 18159197.