https://medicine.ouhsc.edu/academic-departments Parent Page: Academic Departments id: 23109 Active Page: Our Teamid:23118

Section Leadership

Trent Tipple, MD

Trent E Tipple, MD

Professor and Section Chief, Section of Neonatal-Perinatal Medicine
Adjunct Professor of Nutrition Physiology, Biochemistry& Molecular Biology
Children's Health Foundation Reba McEntire Endowed Chair in Neonatology

Medical and Operational Leadership

Kathryn Burge, PhD
Pediatrics

Kathryn Burge, PhD

Assistant Professor of Research


941 Stanton L. Young Blvd. 
Basic Sciences Education Building, Room 235C
Oklahoma City, OK 73104

405-271-5215

Kathryn-Burge@ouhsc.edu


As a member of the Chaaban laboratory, Dr. Burge focuses on developing experimental models, particularly in vitro, through which to study diseases of intestinal inflammation. A recent focus has included mechanisms through which glycosaminoglycans (GAGs) may protect against necrotizing enterocolitis, an inflammatory condition affecting predominantly preterm infants. Primary 3D organoids, 2D organoid-derived monolayers, and rodent models of NEC are utilized to interrogate mechanistic functions of GAGs in this and related contexts.


MyNCBI Publications


Academic Section(s):

Neonatal-Perinatal


Education:

PhD: Baylor University, Department of Biology, Waco, TX
Postdoctoral Fellowship: University of Central Florida College of Medicine, Orlando, FLrsity, Department of Biology, Waco, TX


Clinical/Research Interests:

The Chaaban laboratory works to elucidate the mechanisms through which glycosaminoglycans (GAGs), biologically active components of breast milk, may be protective against intestinal inflammation generally, and neonatal necrotizing enterocolitis (NEC), in particular. Research in the Chaaban laboratory has focused on the many risk factors at play in predisposing infants to developing NEC, including extensive use of antibiotics, lack of breastfeeding, disrupted intestinal microbiome, and the developmentally immature interface between the immune system and the intestinal epithelium in the neonate. Both rodent models and in vitro systems are utilized to further investigate specific attributes of many of these risk factors in the hope that effective therapeutic strategies against NEC and associated diseases will surface.


Select Honors & Accomplishments:

2013 - Great Lakes National Scholarship Award Winner
2012 - Great Lakes National Scholarship Award Winner
2011 - Baylor University Folmar Grant Award
2010 - Baylor University Folmar Grant Award
2009 - Baylor University Graduate Student Award Presentation
2006 - Beta Beta National Biological Honor Society
2002-2006 - Illinois Wesleyan University Merit Scholarship
2004 - NSF Research Experience for Undergraduates (REU)


Select Publications:

  • Chaaban H, Burge K, Eckert J, Keshari R, Silasi-Mansat R, Lupu C, Warner B, Escobedo M, Caplan M, Lupu F. Neutrophil extracellular trap inhibition increases inflammation, bacteremia, and mortality in murine necrotizing enterocolitis. J Cell Molec Med (Online Ahead of Print), 2020. PMID 32515131
  • Gunasekaran A, Eckert J, Burge K, Zheng W, Yu Z, Kessler S, de la Motte C, Chaaban H. Hyaluronan 35 kDa enhances epithelial barrier function and protects against the development of murine necrotizing enterocolitis. Ped Res 87(7), 177-1184, 2019. PMID 31499514. PMC7061074
  • Burge KY, Hannah L, Eckert JV, Gunasekaran A, Chaaban H. The protective influence of chondroitin sulfate, a component of human milk, on intestinal bacterial invasion and translocation. J Human Lactation 35(3):538-549, 2019



Educational Leadership

Erynn Bergner, MD

Erynn Bergner, MD

Assistant Professor
Associate Fellowship Program Director, Section of Neonatal-Perinatal Medicine

Douglas Dannaway, MD

Doug Dannaway, MD

Director of Fellowship
Associate Professor, Section of Neonatal-Perinatal Medicine

Netsanet Kassa, MD

Netsanet Kassa, MD

Assistant Professor
Director of Resident Education, Section of Neonatal-Perinatal Medicine

Research Leadership

Hala Chaaban, MD

​Hala Chaaban, MD

Associate Professor
Adjunct Professor of Nutrition
Associate Director of Translational Research, Section of Neonatal-Perinatal Medicine

Edgardo Szyld, MD, MSc

Edgardo Szyld, MD, MSc

Professor of Research
Director of Clinical and Translational Research Section of Neonatal-Perinatal Medicine
Associate Vice-Chair of Education, Department of Pediatrics

Peter Vitiello, PhD

Peter Vitiello, PhD

Associate Professor
Adjunct Professor of Physiology, Biochemistry & Molecular Biology
Director of Laboratory Research, Section of Neonatal-Perinatal Medicine

Faculty

Lora Bailey-Downs, PhD

Lora Bailey-Downs, PhD

Assistant Professor

Faizah Bhatti, MD

Faizah Bhatti, MD

Associate Professor
Adjunct Associate Professor of Ophthalmology
Member, Oklahoma Center for Neurosciences

Sara Brewer, DO

Sara Brewer, DO

Assistant Professor of Pediatrics, Neonatal-Perinatal Medicine

Kathryn Burge, PhD

Kathryn Burge, PhD

Assistant Professor of Research

Jeffrey Eckert, PhD

Jeffrey Eckert, PhD

Director of Lab Research
Assistant Professor of Research

Jolyn Fernandes, PhD

Jolyn Fernandes, MS, PhD

Assistant Professor of Pediatrics
Associate Director of Metabolomics, Laboratory for Molecular Biology and Cytometry Research
Adjunct Assistant Professor, Biochemistry and Molecular Biology
Member, Harold Hamm Diabetes Center

Arlen Foulks, DO

Arlen Foulks, DO

Assistant Professor
Medical Director of NeoFlight Neonatal Transport Service
Assistant Medical Director, Level 2 NICU at St. Anthony Hospital
Chair of American Osteopathic Board of Pediatrics (AOBP)
Chair of the Neonatal Exam Committee on the AOBP
Adjunct Clinical Assistance Professor in Pediatrics at OSU College of Osteopathic Medicine and Center of Health Sciences

Abhrajit Ganguly, MD

Abhrajit Ganguly, MD

Assistant Professor

Vadim Ivanov, MD

Vadim Ivanov, MD

Assistant Professor
Assistant Medical Director of CCMH NICU
Neonatologist

Erin Jain, MD

Erin Jain, MD

Clinical Assistant Professor
Pediatrician

Barbara Johnson, MD

Barbara Johnson, MD

Assistant Professor
Assistant Director of NICU Resident Education

Samuel Levin, MD

Samuel Levin, MD

Clinical Assistant Professor
 

Marjorie Makoni, MD

Marjorie Makoni, MD

Assistant Professor
Neonatologist

Maxwell Mathias, MD

Maxwell Mathias, MD

Assistant Professor of Pediatrics

Raja Nandyal, MD

Raja Nandyal, MD

Professor of Pediatrics
Medical Director Oklahoma Infant Transition Program (OITP)
Medical Director of Oklahoma Transition Clinic (OTC)
Chairman of OUHSC Neonatal Mortality Committee (NMC)

Gaston Ofman, MD

Gaston Ofman, MD

Assistant Professor

Rita Raman, MD, MS, CNS, JD, MACN, FCLM

Rita Raman, MD, MS, CNS, JD, MACN, FCLM

Professor
Neonatologist

Tavleen Sandhu, MD

Tavleen Sandhu, MD

Clinical Assistant Professor of Pediatrics, Neonatal-Perinatal Medicine
Associate Director of NeoFlight Neonatal Transport Service

Kris Sekar, MD

Kris Sekar, MD

Professor
Neonatologist

Birju Shah, MD, MPH, MBA

Birju Shah, MD, MPH, MBA

Associate Professor
Neonatologist

Frederico Vieira, MD

Frederico Vieira, MD

Assistant Professor

Lauren White, DO

Lauren White, DO

Clinical Assistant Professor
Medical Director of Transition and Labor Consults
Neonatologist

Anne Wlodaver, MD

Anne Wlodaver, MD

Clinical Associate Professor of Pediatrics
Medical Director of SAH Level II NICU