Academic Section(s):
Neonatal-Perinatal Medicine
Education:
Madras Medical College, University of Madras, Madras, India MD - 1974
Pediatric Residency: Polyclinic Medical Center, Harrisburg, PA - 1979
Pediatric Residency, Chief Resident: Georgetown University Hospital, Washington, DC - 1981
Neonatology Fellowship: Georgetown University Hospital, Washington, DC - 1983
Training in ECMO: Children's National Medical Center, George Washington University, Washington DC
Lean Six-Sigma Green Belt: University of Oklahoma, Norman, OK
Board Certification(s):
American Board of Pediatrics
American Board of Pediatrics Sub-Specialty Boards
Neonatal Perinatal Medicine
Clinical/Research Interests:
Dr. Sekar's primary focus has been in pulmonary physiology, surfactant administration, inhaled nitric oxide and non- invasive ventilation. He has participated in numerous trials both investigator initiated and multicenter trials over the last three decades. All these studies have received external funding.
Funding:
Mallinckrodt Pharmaceuticals
Multicenter, Prospectively Defined Observational Registry with Retrospective Data Collection, Evaluating Premature and Term-Near-Term Neonates with Pulmonary Hypertension Receiving Inhaled Nitric Oxide via Invasive or Noninvasive Ventilator Support at US Centers
K C Sekar, Principle Investigator
Chiesi
A multicenter, double blind, randomized, single dose, active-controlled study to investigate the efficacy and safety of synthetic surfactant (chf 5633) in comparison to porcine surfactant (poractant alfa, curosurf®) in the treatment of preterm neonates with respiratory distress syndrome
K C Sekar, Principle Investigator
Pediatric Pharmacy Advocacy Group
Comparison of amikacin pharmacokinetics in neonates pre- and post-doing protocol change.
Primary investigator: Miller JL (PI)
Co-Investigators: Hughes KM, Anderson MP, Sekar KC, Johnson, PN
Ikaria
Potential use of inhaled nitric oxide (iNO) as an adjunct to neonatal resuscitation protocol
KC Sekar, Principal investigator
Pfizer Paraxel
A multi-centre, randomized, placebo-controlled, double-blind, two-armed, parallel group study to evaluate efficacy and safety of iv sildenafil in the treatment of neonates with persistent pulmonary hypertension of the newborn (PPHN) or hypoxic respiratory failure and at risk for PPHN
KC Sekar, Principal investigator
National Institute of Health, NHLBI
Grant # 5R01HL069991-02
“Prolonged Outcome after Nitric Oxide (PrONOx)
Multicenter trial (Derek Angus, PI, University of Pittsburgh)
KC Sekar, Principal Investigator, OUHSC
National Institute of Health - NHLBI
Grant # 1UO1HL64857-01A1 "Inhaled Nitric Oxide for the Prevention of Chronic Lung Disease" Multicenter Trial (Dr. John Kinsella, PI, University of Colorado)
KC Sekar, Principal Investigator, University of Oklahoma
Select Honors & Accomplishments:
Honorary Professor, North West Women and Children’s Hospital, Xi an, China
Honorary Professor, Zhengzhou Children’s Hospital, Zhengzhou, China
Select Publications:
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Amy L. Nguyen, PharmD; Peter N. Johnson, PharmD; Stephen B. Neely, MPH; Kaitlin M. Hughes, PharmD; Kris C. Sekar, MD; Robert C. Welliver, Sr, MD; and Jamie L. Miller, PharmD Comparison of Amikacin Pharmacokinetics in Neonates With and Without Congenital Heart Disease J Pediatr Pharmacol Ther 2021;26(4):372–378
DOI: 10.5863/1551-6776-26.4.372
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Susan M. Bedwell, DNP, MS, APRN, CCNS-N; Barbara Buster, RNC-NIC; Krishnamurthy Sekar, MD. A Randomized Controlled Trial Advances in Neonatal Care Vol. 00, No. 0 • pp. 1–7, 2021
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Satyan Lakshminrusimha, Sylvia F. Gugino, Krishnamurthy Sekar, Stephen Wedgwood,Carmon Koenigsknecht, Jayasree Nair and Bobby Mathew. in Preterm Lambs Inhaled Nitric Oxide at Birth Reduces Pulmonary Vascular Resistance and Improves Oxygenation Children 2021, 8, 378. https://doi.org/10.3390/children8050378
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Vieira F, Makoni M, Szyld E and Sekar K (2021) The Controversy Persists: Is There Qualification Criterion to Utilize Inhaled Nitric Oxide in Pre-term Newborns? Front. Pediatr. 9:631765.doi: 10.3389/fped.2021.631765
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A Makkar, E Szyld, M R. Siatkowski, A Ganguly, MD, KC Sekar, Scope of Telemedicine in Neonatology. Chin J Contemp Pediatr Vol 22 No 5. 2020
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KC Sekar, Edgardo Szyld, Michael McCoy, Anne Wlodaver, Douglas Dannaway, Ashley Helmbrecht, Julee Riley, Amy Manfredo, Michael Anderson, Satyan Lakshminrusimha and Shahab Noori, inhaled nitric oxide as an adjunct to neonatal resuscitation in premature infants: a pilot, double blind, randomized controlled trial. Pediatric Research 2020,87:523-528 https://doi.org/10.1038/s41390-019-0643-x