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Family and Preventive Medicine

Thanh C. Bui, MD, DrPH

Assistant Professor

TSET Health Promotion Research Center – Stephenson Cancer Center 
University of Oklahoma Health Sciences Center
655 Research Parkway, Suite 400
Oklahoma City, OK  73104

(405) 271-8001 ext. 50559

Thanh C. Bui, MD, DrPH, is an Assistant Professor in the Department of Family and Preventive Medicine, and a member of the Stephenson Cancer Center. Dr. Bui has an interdisciplinary background in medicine, global health, health promotion research and cancer prevention research. Dr. Bui's main research interest focuses on behavioral interventions for cancer prevention and control in high-risk populations, including immunizations against oncogenic viruses and tobacco cessation.

His current NCI-funded research projects use mobile health (mHealth) technology to help vulnerable patient populations quit smoking cigarettes in the United States, in Cambodia, and in Lao People's Democratic Republic. Two other studies examine the relationships between tobacco use, marijuana use, oncogenic (co)infections, and several health outcomes among Americans. Other research interests of Dr. Bui include sexual health promotion to prevent cancers (e.g., HPV vaccination) and the application of innovation generation tools to promoting cancer prevention behaviors.

He has extensive experience in working with vulnerable high-risk populations, such as people living with HIV/AIDS, sex workers, and people with low socioeconomic status. He also has strong partnerships with senior investigators and health practitioners in developing countries in Southeast Asia, such as Vietnam, Lao PDR and Cambodia.

Academic Section(s):

OUFMC Research Division


DrPH: Health Promotion and Behavioral Sciences, The University of Texas Health Science Center, Houston, TX, 2006 – 2010.

MPH: Global Health, Yale University - School of Public Health, New Haven, CT, 2004 – 2006.

MD: Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam, 1996 – 2002.


Postdoctoral Fellowship in Innovation in Cancer Prevention Research, The University of Texas Health Science Center at Houston, Houston, TX, 2012 – 2014.

Postdoctoral Fellowship in International Training on AIDS Research, The University of Texas Health Science Center at Houston, Houston, TX, 2010 – 2012.

Clinical/Research Interests:

  • Behavioral interventions to prevent oncogenic sexually transmitted infections (particularly HIV and HPV)
  • Sexual health promotion
  • HPV vaccination
  • Tobacco cessation in vulnerable populations (e.g., people living with HIV)
  • Global health



1 U01 CA261598-01 (MPI: Bui, Vidrine)
Ending Tobacco Use through Interactive Tailored Messaging for Cambodian People Living with HIV/AIDS (EndIT).
This research project aims to evaluate efficacy and cost-effectiveness of our theoretically and empirically based mobile health (mHealth) smoking cessation intervention for smokers living with HIV in Cambodia. This mHealth approach includes a fully automated, interactive, personalized, smartphone-delivered intervention for behavioral treatment.

1 R21 CA253600-01 (R21/R33) (PI: Bui)
09/01/2020 – 08/30/2025
Mobile Health Technology for Personalized Tobacco Cessation Support in Laos (Support Laos)
This research project aims to adapt and evaluate the efficacy of our theoretically and empirically based mobile health (mHealth) technology to help people quit smoking cigarettes in Lao People’s Democratic Republic.

R01CA243552 (PI: Damon Vidrine)
09/01/2019 – 08/31/2024
Randomized Trial of Automated Video-Assisted Smoking Treatment for People Living with HIV
The purpose of this randomized controlled trial is to evaluate a fully automated smartphone smoking-cessation intervention for HIV-positive smokers.
Role: Co-investigator, Site PI

Stephenson Cancer Center - Pilot Award (PI: Bui)
07/01/2018 – 04/30/2021
Promoting human papillomavirus vaccine uptake in high-risk adults
This pilot study aims to determine the preliminary efficacy of an innovative, theory-based approach that combines partner referral and peer-driven intervention to increase human papillomavirus vaccine uptake in eligible high-risk adults in Oklahoma City, OK, USA.

NCORP-Gogoi-GY7NRG Oncology - NCI Community Oncology Research Program (NCORP) Pilot Award (PI: Gogoi, Radhika)
Relational Agents in HPV Vaccine Education
This project aims to explore the efficacy of a computerized simulated interactable healthcare provider in educating survivors of an HPV related disease (e.g., cervical cancer) about the importance of HPV vaccination and engaging them in promoting HPV vaccination. Study sites include the NCI-designated Stephenson Cancer Center at the University of Oklahoma Health Sciences Center and the Karmanos Cancer Institute (KCI) at Wayne State University.
Role: Co-investigator, Site PI

NCI SBIR PHS 2021-1      (PI: Amarasingham)
Screening for Social Determinants of Health and Interventions to Improve Outcomes in the Cancer Patient Population.
The goal of this project is to design and launch an Information Technology (IT) platform that enables easy incorporation of Social Determinants of Health data into cancer patients’ electronic health records in order to improve coordination of care for cancer patients in multiple cancer centers across the US.
Role: Co-investigator

Completed (past 5 years):

Presbyterian Health Foundation - Seed Grant (PI: Bui)
07/01/2018 – 06/30/2020
Using partner referral to increase human papillomavirus vaccine uptake
The purpose of this mixed-methods pilot study is to determine the feasibility of an innovative, evidence-based approach—partner referral—to increase HPV vaccine uptake in people living with HIV in Oklahoma City, OK, USA.

Select Publications:

For a list of Dr. Bui's publications, please visit THIS LINK.


  • Le P, Bui TC, Abramowitz J, Herman WH, Misra-Hebert AD, Rothberg MB. Trends in use of high-cost antihyperglycemic drugs among US adults with type 2 diabetes. Journal of General Internal Medicine 2022. DOI: 10.1007/s11606-022-07621-2
  • Gogoi RP, Wallbillich JJ, Winer I, Morris R, Ritchie C, Larson S, Walker J, Bickmore T, Spencer E, Jang H, Kim S, Phalore J, Bui TC. Computer-animated relational agents in human papillomavirus vaccination education. Obstetrics & Gynecology 2022; 139(5): 913-915. DOI: 10.1097/AOG.0000000000004763
  • Kulkarni SV, Xangsayarath P, Douangvichith D, Siengsounthone L, Phandouangsy K, Tran LT, Lee PH, Bui TC. Secondhand smoke exposure in Lao People's Democratic Republic: Results from the 2015 National Adult Tobacco Survey. International Journal of Public Health 2021; 66: 1604436. DOI: 10.3389/ijph.2021.1604436
  • Vidrine DJ, Bui TC, Businelle MS, Shih YT, Sutton SK, Shahani L, Hoover DS, Bowles K, Vidrine JI. Evaluating the efficacy of automated smoking treatment for people with HIV: protocol for a randomized controlled trial. JMIR Research Protocols. Epub 11-17-2021.   DOI: 10.2196/33183
  • Tran Y, Tran H, Tran L, Nguyen D, Le C, Bui T. Comparison of clinical outcomes of implantable collamer lens versus femtosecondlaser in situ keratomileusis and small incision lenticule extraction for moderate-to-high myopia and myopic astigmatism correction. Asian Journal of Ophthalmology. April 2021; 17(4):400-415.  DOI: 10.35119/asjoo.v17i4.714
  • Bui TC, Sopheab H, Businelle MS, Chhea C, Ly SP, Vidrine JI, Thol D, Frank-Pearce S, Vidrine DJ. Mobile-health intervention for smoking cessation among Cambodian people living with HIV: A mixed-methods pilot study. AIDS Care. Epub 03-10-2021.   DOI: 10.1080/09540121.2021.1887443
  • Bui TC, Pineiro B, Vidrine DJ, Wetter DW, Frank-Pearce SG, Vidrine JI. Quitline treatment enrollment and cessation outcomes among smokers linked with treatment via Ask-Advise-Connect: Comparisons among smokers with and without HIV. Nicotine & Tobacco Research. August 2020; 22(9): 1640-1643. Epub 12-08-2019. DOI: 10.1093/ntr/ntz227
  • Bui TC, Xangsayarath P, Douangvichith D, Siengsounthone L, Phandouangsy K, Tran LT, Businelle, MS. Factors associated with cigarette smoking cessation in Lao People’s Democratic Republic: results from the 2015 National Adult Tobacco Survey. International Journal of Environmental Research and Public Health.  July 2020; 17(14): 4953.  DOI: 10.3390/ijerph17144953
  • Sopheab H, Suy S, Chhea C, Chhit S, Mun P, Bui TC. Psychological distress among Cambodian people who use drugs. Drug and Alcohol Review.  January 2020; 39(1): 66-70.  DOI: 10.1111/dar.13000