Parent Page: Academic Departments id: 23019 Active Page: Faculty id:23020


John E. Grunow, M.D.

John E Grunow, M.D.

Professor, Pediatric Gastroenterology

OU Children's Physicians
1200 N Phillips Ave, Suite 9500
Oklahoma City, OK 73104
Phone (405) 271-6549
Fax (405) 271-7866

Past Section Chief, Pediatric Gastroenterology, Hepatology and Nutrition


Valparaiso University, Valparaiso, Indiana; B.S., Biology & Chemistry, 1967-1971
University of Texas, Southwestern Medical School, Dallas, Texas; M.D. 1971-1975
Intern and Resident: Department of Pediatrics, Oklahoma Children's Memorial Hospital, OKC, Ok 1975-1977
Chief Resident: Department of Pediatrics, Oklahoma Children's Memorial Hospital, OKC, OK 1977-1978
Fellowship: Section of Pediatric Gastroenterology, Oklahoma Children's Memorial Hospital, OKC, OK 1978-1980
Sabbatical: Pediatric Clinical Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada 1991-1992

Board Certification(s):

Diplomat, National Board of Medical Examiners, #157540, 1976
Board Certified, American Board of Pediatrics, #040469, 1981
Subspecialty Board Certified, American Board of Pediatrics, Pediatric Gastroenterology, #098, 1990, Rectified, 1997, 2003, MOC certified 2014
Licensure, Oklahoma, #11004, 1976

Clinical/Research Interests:

Inflammatory Bowel Disease

Select Honors & Accomplishments:

The CMRI Griffin Family Endowed Research Chair in Pediatric Gastroenterology 2016 - Present
OU Medicine Award for Outstanding Patient Service 2017

Select Publications:

  • Grunow JE, Lubert RA, Ferguson MJ and Gaulden MD.  Preferential decrease in thymus dependent lymphocytes during storage at 4°C in anticoagulant.  Transfusion 16(6):610-615, Nov-Dec, 1976.
  • Grunow JE.  Gastroesophageal reflux in Rubinstein-Taybi Syndrome.  J Pediatr Gastroenterol Nutr, 1(2):273-274, 1982.
  • Bodensteiner JB and Grunow JE.  Gastroparesis in neonatal myotonic dystrophy.  Muscle and Nerve, 7:486-487, 1984
  • Figueroa-Colon R, Grunow JE, Torres-Pinedo R and Rettig PJ.  Group A streptococcal proctitis and vulvovaginitis in a pre-pubertal girl.  Pediatr Infec Dis, 3(5)439-442, 1984
  • Jolley SG, Tunell WP, Carson JA, Smith EI and Grunow JE.  The accuracy of abbreviated esophageal pH monitoring in children.  J Pediatr Surg, 19(6):848-854, 1984
  • Grunow JE, Dunton SF, and Waner JL.  Human rotavirus-like particles in a hepatic abscess.  J Pediatr, 106(1):73-76, 1985
  • Grunow JE, and Howard S.  A randomized study of oral metoclopramide in small bowel biopsy of infants and children.  J Pediatr Gastroenterol Nutr 7(1):64-67, 1988..
  • Figueroa-Colon R and Grunow JE.  Randomized study of premedication for esophagogastroduodenoscopy in children and adolescents.  J Pediatr Gastrenterol Nutr 7:359-366, 1988
  • Marks WA, Morris MP, Bodensteiner JB, Grunow JE, Bobele GB, Hille MR, Tuggle D.  Gastritis and valproate therapy.  Arch Neurol 45:903-905, 1988
  • Mitchell DS, Stacy TM, Grunow JE, Leonard JC.  Scintigraphic detection of an occult abdominal bleed in a child.  Clin Nucl Med 13(7):546-548, 1988.
  • Grunow JE, Al-Hafidh AS, Tunell WP.  Gastroesophageal reflux following percutaneous endoscopic gastrostomy in children.  Journal of Pediatric Surgery, 24(1): 42-45, 1989.
  • Grunow JE, Christenson JC, Moutos D.  Contamination of enteral nutrition systems during prolonged intermittent use. J Parenter Enter Nut 13(1):23-25, 1989.
  • Grunow JE, Azcue MP, Berall G, Pencharz PB.  Energy expenditure in cystic fibrosis during activities of daily living.  J Pediatr 122:243-246, 1993.
  • Alaswad B, Toubas P, Grunow J.  Environmental Tobacco Smoke Exposure and Gastroesophageal Reflux in Infants with Apparent Life - threatening Events.  J. Oklahoma State Medical Association 89:233-237, 1996.
  • Yaseen M, Steele M, Grunow J.  Nonendoscopic removal of percutaneous endoscopic gastrostomy tubes:  morbidity and mortality in children.  Gastrointest Endosc 44:235-8, 1996.
  • Barrie MT, Backues KA, Grunow J, Nitschke R. Acute lymphocytic leukemia in a six-month-old
  • western lowland gorilla (Gorilla gorilla gorilla). Journal of Zoo & Wildlife Medicine 30:268-72, 1999.
  • Darling PB, Grunow J, Rafii M, Brookes S, Ball RO, Pencharz PB. Threonine dehydrogenase is a
  • minor degradative pathway of threonine catabolism in adult humans. American Journal of Physiology-Endocrinology & Metabolism  278:E877-84, 2000.
  • Orenstein SR, Blumer JL, Faessel HM, McGuire JA, Fung K, UK LI B, Lavine JE, Grunow JE, Treem, WR, Ciociola AA. Ranitidine, 75 mg, over-the-counter dose: pharmacokinetic & pharmacodynamic effects in children with symptoms of gastroesophageal reflux. Aliment Pharmacol Ther 16(5):899-907, 2002.
  • Altaf, MA and Grunow JE. Atypical Presentations of Celiac Disease: Recurrent Intussusception and  
  • Pneumatosis Intestinalis. Clin Pediatr. 47(3):289-292, 2008.
  • Short pediatric Crohn’s disease activity index for quality improvement and observational research.
  • Crandall W. Kappelman MD. Colletti RB. Liebowitz I. Grunow JE. Ali S. Baron HI. Berman JH. Boyle B. Cohen S. del Rosario F. Denson LA. Duffy L. Integlia MJ. Kim SC. Milov D. Patel AS. Schoen BT. Walkiewicz D. Margolis P. Inflammatory Bowel Diseases.  17(1):450-7, 2011 Jan. UI: 20602466
  • Prevalence and epidemiology of overweight and obesity in children with inflammatory bowel disease.Long MD. Crandall WV. Leibowitz IH. Duffy L. del Rosario F. Kim SC. Integlia MJ. Berman J. Grunow J. Colletti RB. Schoen BT. Patel AS. Baron H. Israel E. Russell G. Ali S. Herfarth HH. Martin C. Kappelman MD. ImproveCareNow Collaborative for Pediatric IBD. Inflammatory Bowel Diseases. 12(10):2162-8, 2011 Oct. UI: 21910178
  • Crandall WV, Margolis PA, Kappelman MD, King EC, Pratt JM, Boyle BM, Duffy LF, Grunow JE, Kim SC, Leibowitz I, Schoen BT, Colletti RB, for the ImproveCareNow Collaborative.  Improved outcomes in a quality improvement collaborative for pediatric inflammatory bowel disease.  Pediatrics 129(4):e1030-e1041, 2012.
  • Early Presentation of Low Phospholipid-Associated Cholelithiasis Syndrome. Bitar A, Grunow J, Steele M, Sferra TJ. Clin Pediatr. 2013 Feb 19. PMID: 23426229.
  • Health care burden of Clostridium difficile infection in hospitalized children with inflammatory bowel disease.
  • Pant C, Anderson MP, Deshpande A, Altaf MA, Grunow JE, Atreja A, Sferra TJ.
  • Inflamm Bowel Dis. 2013 Apr;19(5):1080-5. doi: 10.1097/MIB.0b013e3182807563.PMID:23478808
  • Seasonality and pediatric inflammatory bowel disease. Lee GJ1, Dotson JL, Kappelman MD, King E, Pratt JM, Colletti RB, Bistrick S, Burkam JL, Crandall WV; ImproveCareNow Network.(Collaborator – J Grunow) J Pediatr Gastroenterol Nutr. 2014 Jul;59(1):25-8. doi: 10.1097/MPG.0000000000000362.
  • There's an App for That—Measuring Disease-Specific Knowledge and Mood in Children With Inflammatory Bowel Disease. Jeanne Tung, John Grunow, Noel J. Jacobs. Gastroenterology 05/2014; 146(5). DOI:10.1016/S0016-5085(14)62812-2
  • Severity of Illness and Quality of Life Over Time in Pediatric Inflammatory Disease Patients.
  • Erin Swedish, Ryan T. Blucker, John Grunow, Kristina Suorsa, Noel J. Jacobs.
  • Gastroenterology 04/2015; 148(4). DOI:10.1016/S0016-5085(15)32140-5
  • Pilot Development of an Electronic Pediatric Inflammatory Bowel Disease Quiz Game.
  • Tung J, Grunow JE, Jacobs N. J Pediatr Gastroenterol Nutr. 2015 Sep;61(3):292-6. doi: 10.1097/MPG.0000000000000788.PMID: 25793902
  • Quality Items Required for Running a Paediatric Inflammatory Bowel Disease Centre: An
  • ECCO Paper Dan Turner,a Adam Carle,b Steven J. Steiner,c Peter A. Margolis,b Richard B. Colletti,d Richard K. Russell,e Arie Levine,f Kaija-Leena Kolho,g Frank M. Ruemmele;h the ImproveCareNow Network*; Journal of Crohn's and Colitis, 2017, 981–987doi:10.1093/ecco-jcc/jjx036
  •  The Use of Concomitant Immunomodulators with Adalimumab Therapy in Pediatric Crohn’s Disease. Keith J. Benkov1#*, George H. Russell2, Charles M. Samson3, Steven J. Steiner4, Eileen C. King5, Jesse Pratt5, Samantha F. Eichner6, Richard B. Colletti7, and the Improve Care Now Network# JSM Arthritis 2(2): 1026 (2017)
  • Gamwell, K. L., Baudino, M., Bakula, D. M., Sharkey, C. S., Roberts, C. M., Grunow, J., Jacobs, N., Gillaspy, S., Mullins, L. L., & Chaney, J. M. (2018). Stigma, thwarted belongingness, and depressive symptoms in youth with inflammatory bowel disease (IBD). Inflammatory Bowel Diseases, 24(5), 960-965.
  • Baudino, M., Gamwell, K., Roberts, C., Perez, M., Grunow, J., Jacobs, N., Gillaspy, S., Edwards, C., Mullins, L., & Chaney, J. (in press). Disease severity and depressive symptoms in adolescents with IBD: The mediating role of parent and youth illness uncertainty. Journal of Pediatric Psychology. 2018, 1-9; doi: 10.1093/jpepsy/jsy091
  • Roberts, C., Gamwell, K., Baudino, M., Perez, M., Delozier, A., Sharkey, M., Grant, D., Grunow, J., Jacobs, N., Gillaspy, S., Mullins, L., & Chaney, J. (under review). Youth and parent illness appraisals and adjustment in pediatric inflammatory bowel disease. Journal of Child Health Care.