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Lewis A Hassell, MD

Lewis A. Hassell, MD

Professor of Pathology

Professor of Excellence in Anatomic Pathology

Director, Anatomic Pathology

The University of Oklahoma 
Health Sciences Center
Presbyterian Tower
700 N.E. 17th St
Lower Level, Pathology Suite
Oklahoma City, OK 73104



  • Brigham Young University
    Provo, UT 
    B.S., 1978, Graduated Summa Cum Laude
  • University of Utah
    Salt Lake City, UT
    MD, 1982
  • University of California
    San Francisco, CA
    Visiting Fellowship in Nuclear Medicine, 1987-88
  • Massachusetts General Hospital
    Boston, MA
    Resident in Clinical & Anatomic Pathology, 1982-86 
    Chief Resident in Pathology, 1984

Board Certification(s):

  • American Board of Pathology, Cytopathology
  • American Board of Pathology, Anatomic and Clinical

Clinical/Research Interests:

My current interests include process improvements, error reduction and quality gains in laboratory workflow, and structural and organizational alignment for optimization of work teams in a variety of medical environments. Applying modern business theory (such as Lean, Six Sigma, high performance work teams) to laboratory and medical processes has yielded tremendous results among early adopting settings. We are seeking to find solutions to the human, fiscal and technological challenges that such changes present.

I am also interested in ways of applying process improvement to enhance access to care, and specifically pathology services, to underserved populations domestically and internationally. The interface of current status quo with potentially disruptive technology or processes, and how to use these fault lines to open up access rather than restrict it are challenges we are working on solving.

Select Publications:

  1. Weiss RL, Hassell LA, Parks ER. Progress toward improved leadership and management training in pathology. Arch Pathol Lab. Med April 2014;138(4):492-497 .2013-0288-RA. PMID:23777420

  2. Hassell LA, Wagar EA.  Twenty (foward looking) questions. J Pathol Inform 2014; 5:27.

  3. Parwani AV, Hassell L, Glassy E, Pantanowitz L: Regulatory barriers surrounding the use of whole slide imaging in the United States of America. J Pathol Inform 2014, 5:38 (21 October 2014).

  4. Guo R, Fierro-Fine A, Goddard L, Russell M, Chen J, Liu CZ, Fung KM, Hassell LA. Increased expression of melanoma stem cell marker CD271 in metastatic melanoma to the brain. Int J Clin Exp Pathol. 2014 Dec 1;7(12):8947-51. eCollection 2014. PMID: 25674270.  

  5. Husain S, Hassell LA. Microsatellite instability (MSI) testing in extra-colonic tumors. [Mini Review] J Clin Exp Pathol 5:221. 2015 Mar 15; Vol 5; Iss 3. doi: 10.4172/2161-0681.1000221.

  6. Williams CL, Bjugn R, Hassell LA. Current status of discrete data capture in synoptic surgical pathology and cancer reporting. [Review] Pathol Lab Med Int. 2015 June 9:7;11-22.

  7. Yin F, Han G, Bui MM, Gibbs J, Martin I, Sundharkrishnan L, King L, Jabcuga C, Stuart LN, Hassell LA. Educational value of digital whole slides accompanying published online pathology journal articles: A multi-institutional study. 2016 Apr 26. [Epub ahead of print] doi: 10.5858/arpa.2015-0366-OA. PMID: 27116087

  8. Deel C, Hassell L. Liposclerosing myxofibrous tumor: A review. [Resident Short Review] Arch Pathol Lab Med. 2016 May;140(5):473-6. doi: 10.5858/2014-0503-RS. PMID: 27128305

  9. Vuong HG, Kondo T, Pham TQ, Oishi N, Mochizuki K, Nakazawa T, Hassell L, Katoh R. Prognostic significance of diffuse sclerosing variant papillary thyroid carcinoma: a systematic review and meta-analysis. Eur J Endocrinol. April 2017;176(4):431-439, doi: 10.1530/EJE-16-0863. PMID: 28183787

  10. Vuong HG, Altibi AMA, Duong UNP, Ngo HTT, Pham TQ, Fung KM, Hassell L. BRAF mutation is associated with an improved survival in glioma-a systematic review and meta-analysis. Mol Neurobiol. 2017 May 22. doi: 10.1007/s12035-017-0599-y. [Epub ahead of print] PMID: 28534272

Publication of Clinical Guidelines

“Clinical Guidelines for Telepathology, August, 2014,” approved by the Board of Directors of the American Telemedicine Association. Authors: Liron Pantanowitz, Chair, Kenneth Bloom, Alexis Carter, Kim Dickenson, Andrew Evans, Lewis Hassell, Walter Hendricks, Keith Kaplan, Elizabeth Krupinski, Jochen Lennerz, Amanda Lowe, Anil Parwani, Michael Riben, Daniel Smith, Ronald Weinstein, and David Wilbur.