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Dean Myers, PhD
Obstetrics and Gynecology

Dean Myers, PhD

Professor

Vice Chair for Research (Basic)

John W. Records Chair in Maternal-Fetal Medicine

Director of Research, MFM Fellowship

Member, Harold Hamm Diabetes Center


Education:

  • BS degree in Animal Science from Fort Hays State University (KS) in 1981
  • MS degree in Reproduction from University of Wyoming in 1983
  • PhD degree in Reproduction/Biochemistry from University of Wyoming in 1987
  • NIH Post-doctoral Fellowship at Laboratory for Pregnancy and Newborn Research at Cornell University from 1987-1990


Clinical/Research Interests:

  • Impact of gestational hypoxia on fetal physiology, endocrinology and adipose development
  • Maternal obesity and Western diet epigenetic fetal programming for childhood and adult disease in the Non-human primate, Papio anubis (Olive baboon)
  • Maternal Zika virus infection and fetal CNS pathology in the Olive baboon


Select Honors & Accomplishments:

  • President’s Associates Presidential Professorship, OUHSC 2009-current
  • Core Member: Harold Hamm Diabetes Center, OUHSC 2014-current
  • Editorial Board, Frontiers in Endocrinology 2017-current
  • Chair and ad hoc reviewer, NIH CSR, Special Emphasis Panel: Pediatric and Obstetric Pharmacology and Therapeutics. ZRG1 ENMR-S (55)R, 11/2020
  • Chair and ad hoc reviewer and Chair, NIH CSR, Special Emphasis Panel: Neurodevelopment and Neurological Disorders. ZRG1 BDCN-W (90)S, 11/2020
  • Ad hoc reviewer, NIH CSR, Special Emphasis Panel: Endocrine and Reproductive Biology. ZRG1 ENMR-F02, 7/2019
  • Ad hoc reviewer, March of Dimes, Novel Discovery Review Panel 6/2019
  • Chair and ad hoc reviewer, NIH CSR, ZRG1 EMNR-S (55) Special Emphasis Panel: Translational Research in Pediatric and Obstetrical Pharmacology and Therapeutics 3/2109
  • Chair and Ad hoc reviewer, NIH CSR 10 ZRG BDCN-Q(02) Special Emphasis Panel: Neurobiology of brain degenerative disorders, autoimmune diseases and viral infection-2, 7/2019
  • Chair, NIH CSR ZRG1 BDCN-E (04), Special Emphasis Panel: Neurobiology of brain degenerative disorders, autoimmune diseases and viral infection-1, 6/2018
  • Chair and ad hoc reviewer, NIH CSR, ZRG1 EMNR-S, Special Emphasis Panel:  Translational Research in Pediatric and Obstetrical Pharmacology and Therapeutics. PAR-17-187-189, 3/2018
  • Ad hoc, NIH CSR, NAIAD Program Project Applications (P01) ZAI1 RRS-M J1 (Zika), 9/2017
  • NIH CSR Rapid assessment of Zika virus complications. ZAI1 M M3-RG, 5/2017
  • NIH CSR Dual Purpose with Dual Benefit: Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Animal Species. 2017/05 ZRG1 IDM-N(50)S, 3/2017
  • NIH CSR Pregnancy and Neonatology (PN) Study Section, 10/2016
  • NIH CSR Special Emphasis Panel, PAR13-309-311: Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics, ZRGI EMNR-S, 6/2016
  • NIH CSR Special Emphasis Panel, ZRGI EMNR-A, 7/2015
  • NIH CSR Integrative, Clinical Endocrinology and Metabolism (ICER) Study Section, 2/2015
  • NIH CSR Pregnancy and Neonatology (PN) Study Section, 6/2014
  • NIH CSR Endocrinology, Metabolism, Nutrition and Reproductive Sciences Small Business/Technology Transfer (SBIR/STTR) Study Section, 6/2014
  • Chair and Reviewer, NIH CSR Endocrinology, Metabolism, Nutrition and Reproductive Sciences Small Business/Technology Transfer (SBIR/STTR) Study Section, Special Emphasis Panel, NIH CSR ZRG1 EMNR-S 11 B, 12/2013
  • Chair, NIH CSR PAR Panel: Research in Biomedicine and Agriculture Using Agriculturally Important Domestic Animal Species. ZRG1 EMNR-D, 3/2012
  • NIH CSR Special Emphasis Panel: Developmental Pharmacology, NIH ZRG1, CB-L, 8/2011
  • NIH CSR NICHD Program Project Review, ZHD1 DSR-Z, 4/2011
  • NIH CSR NICHD Program Project Review, ZHD1 DSR-Z, 4/2010
  • NIH CSR Neuroendocrin., Neuroimmun. & Behavior (NNB) Study Section, 2/2010
  • NIH CSR Neuroendocrin., Neuroimmun. & Behavior (NNB) Study Section, 10/2009
  • NIH CSR Neuroendocrin., Neuroimmun. & Behavior (NNB) Study Section, 6/2009
  • Regular Member, NIH CSR Pregnancy and Neonatology (PN) Study Section 2008-2012
  • NIH CSR, Special Emphasis Panel-Pregnancy and Developmental Biology, 7/2008
  • NIH CSR, Special Emphasis Panel-Pregnancy and Neonatology, EMNR ZRG1, 7/2007
  • NIH CSR Pregnancy and Neonatology (PN) study section, 2/2007
  • oc mem HOcNIMH CSR Conte Centers for Neuroscience, 2/2005
  • NIH CSR Human Embryology and Development (HED-1), 2/2002


Select Publications:

Complete List of Published Work in My Bibliography:

https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/47967746/?sort=date&direction=ascending

  • Gurung S, Nadeau H, Maxted M, Peregrine J, Reuter N, Norris A, Edwards R, Hyatt K, Singleton K, Marti A, Parks WT, Papin JF, Myers DA. 2020. Maternal Zika virus (ZIKV) infection following vaginal inoculation with ZIKV-infected semen in the timed pregnant olive baboon, J. Virology 94(11)e00058-20. PMID: 43188737
  • Myers DA, Singleton K, Hyatt K, Kaushal KM, Ducsay CA. 2020. Long term hypoxia during gestation alters perirenal adipose tissue gene expression in the lamb. Adipocyte. Dec;9(1):223-233. doi: 10.1080/21623945.2020.1763726.PMID: 32403966
  • Gurung S, Reuter N, Preno AN, Dubaut JP, Nadeau H, Hyatt K, Singleton K, Maxted M, Parks WT, Papin JF, Myers DA. 2019. Zika virus infection at mid-gestation results in fetal cerebral cortical injury and fetal death in the olive baboon. PLoS Pathogens 15(1): e1007507.   https://doi.org/10.1371/journal.ppat.1007507
  • Peregrine J., Gurung S., Lindgren M.C., Husain S, Zavy M.T., Myers D.A., Papin J.F. 2019. Zika virus infection, reproductive organ targeting, and semen transmission in the male olive baboon. J. Virology. PMID: 3159777
  • Scifres C.M., Mead-Harvey C., Nadeau H., Reid A., Pierce S., Feghali M., Myers D., Fields D., Stoner J.A. 2019. Intensive Glycemic Control in Gestational Diabetes Mellitus: A Randomized Controlled Clinical Feasibility Trial. Am. J. Obstet. Gynecol., Maternal-Fetal-Medicine Nov;1(4):100050. doi: 10.1016/j.ajogmf.2019.100050. PMID: 3334584
  • Gurung S, Preno AN, Dubaut JP, Nadeau H, Hyatt K, Reuter N, Nehete B, Wolf RF, Nehete P, Dittmer DP, Myers DA, Papin JF. 2018. Translational model of Zika virus infection in baboons. J. Virology Jun 6. pii: JVI.00186-18. doi: 10.1128/JVI.00186-18. PMID:2987524
  • Pierce S., Bakker R., Myers D.A., Edwards R.K. 2018. Clinical insights for cervical ripening and labor induction using prostaglandins. AJP Reproduction. Oct;8(4):e307-e314. doi: 10.1055/s-0038-1675351. Epub 2018 Oct 29. PMID:30377555
  • Pierce S, Roberson AE, Hyatt K, Singleton K, Deschamps D, Myers DA. 2017. Interaction between progesterone and interleukin1eta in modulating progesterone receptor expression and the inflammatory phenotype in human cervical fibroblasts. Reprod. Sci. (PMID: 28820025)
  • Bakker R., Pierce S, Myers D. 2017. The role of prostaglandins E1 and E2, dinoprostone, and misoprostol in cervical ripening and the induction of labor: a mechanistic approach. Arch. Gynecol. Obstet. Aug;296(2):167-179. doi: 10.1007/s00404-017-4418-5. Epub 2017 Jun 5.PMID: 28585102
  • Vargas, V., Gurung, S., Grant, R., Hyatt, K., Singleton, K., Suanders, D., Njoku, C., Towner, R., Myers, D. A. 2017. Gestational hypoxia disrupts the neonatal leptin surge and programs hyperphagia and obesity in male offspring in the Sprague-Dawley rat. PLOSone. PMID: 28957383.
  • Vargus V. Singleton K, Kaushal KM, Myers DA, Ducsay CA. 2017. Expression of StAR and Key Genes Regulating Cortisol Biosynthesis in Near Term Ovine Fetal Adrenocortical Cells: Effects of Long Term Hypoxia. Reprod. Sci.
  • Gurung S. Agbaga M-P, Myers DA. 2016. Cognitive differences between Sprague-Dawley rats selectively bred for sensitivity or resistance to diet induced obesity. Behavioral Brain Research. 311:122-30. PMID: 27173431
  • Myers DA, Singleton K, Kenkel C, Kaushal KM, Ducsay CA. 2016. Gestational hypoxia modulates expression of corticotropin releasing hormone and arginine vasopressin in the hypothalamic paraventricular nucleus in the ovine fetus. Physiological Reports. Jan; 4(1). pii:e12643.doi: 10.14814/phy2.12643.
  • Jackson D, Deschamps D, Myers D, Fields D, Knudtson E, Gunatilake R. 2016. Fetal epicardial fat thickness in diabetic and non-diabetic pregnancies: a retrospective cross sectional study. Obesity. Jan; 24(1):167-71. PMID: 26638197